1-Methylcyclopropyl 4-nitrophenyl carbonate

Base Information

• Chemical Name: 1-Methylcyclopropyl 4-nitrophenyl carbonate
• CAS No.: 1046817-22-4
• Molecular Formula: C11H11NO5
• Molecular Weight: 237.212
• Hs Code.: 2920909090
• Mol file: 1046817-22-4.mol

Synonyms:1-methylcyclopropyl 4-nitrophenyl carbonate

Chemical Property of 1-Methylcyclopropyl 4-nitrophenyl carbonate

Chemical Property:

• Melting Point: 46-48℃
• PSA: 81.35000
• Density: 1.35±0.1 g/cm3 (20 oC 760 Torr)
• LogP: 3.18590
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

1-Methylcyclopropyl(4-nitrophenyl)carbonate 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Methylcyclopropyl 4-nitrophenyl carbonate

There total 4 articles about 1-Methylcyclopropyl 4-nitrophenyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1-methylcyclopropanol (29526-99-6) + 4-Nitrophenyl chloroformate (7693-46-1) → 1-methylcyclopropyl (4-nitrophenyl)carbonate (1046817-22-4)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 1.5h;

DOI:10.1016/j.tetlet.2011.04.027

Reference yield: 79.0%

→ 1-methylcyclopropyl (4-nitrophenyl)carbonate (1046817-22-4)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 0.166667h; Inert atmosphere;

In dichloromethane; at 20 ℃; for 48h; Inert atmosphere;

Reference yield:

1-methylcyclopropanol (29526-99-6) + 4-Nitrophenyl chloroformate (7693-46-1) → 1-methylcyclopropyl (4-nitrophenyl)carbonate (1046817-22-4) + bis-(p-nitrophenyl) carbonate (5070-13-3)

Guidance literature:

With pyridine; In dichloromethane-d2; at 20 ℃;

DOI:10.1055/s-0033-1338504

upstream raw materials:

1-methylcyclopropanol

4-Nitrophenyl chloroformate

triethylamine

Downstream raw materials:

1-methylcyclopropyl 4-(4-((4-(methylsulfonyl)piperazin-1-yl)methyl)phenoxy)piperidine-1-carboxylate

1-methylcyclopropyl 4-((3,5-difluoro-4'-(methylsulfonyl)biphenyl-4-yloxy)methyl)piperidine-1-carboxylate

1-methylcyclopropyl 4-((4-bromo-2,6-difluorophenoxy)methyl)piperidine-1-carboxylate

1-methylcyclopropyl 4-{5-cyano-4-[(2,5-difluorophenoxy)methyl]-1H-pyrazol-1-yl}piperidine-1-carboxylate