Ginsenoside Rg5

Base Information

• Chemical Name: Ginsenoside Rg5
• CAS No.: 74964-14-0
• Molecular Formula: C₄₂H₇₀O₁₂
• Molecular Weight: 767.011
• Mol file: 74964-14-0.mol

Synonyms:Ginsenoside Rg5; G-Rg5; beta-D-Glucopyranoside, (3beta,12beta,20E)-12-hydroxydammara-20(22),24-dien-3-yl 2-O-beta-D-glucopyranosyl-; (8xi,9xi,12alpha,13xi,14beta,17beta)-17-[(1E)-1,5-dimethylhexa-1,4-dien-1-yl]-12-hydroxy-4,4,7,10,14-pentamethylgonan-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside

Chemical Property of Ginsenoside Rg5

Chemical Property:

• Vapor Pressure: 1.93E-34mmHg at 25°C
• Boiling Point: 859.7°C at 760 mmHg
• PKA: 12.85±0.70(Predicted)
• Flash Point: 473.7°C
• Density: 1.28g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ginsenoside Rg5

There total 4 articles about Ginsenoside Rg5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ginsenoside Rb1 → [12β,20(S),25-trihydroxydammar-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside] (592550-52-2) + [12β,20(R),25-trihydroxydammar-3-O-β-D-glucopyranosyl-β-(1→2)-β-D-glucopyranoside] + 20(R)-ginsenoside Rg3 (38243-03-7) + ginsenoside Rg3 (14197-60-5,38243-03-7,126252-51-5) + 3β,12β-dihydroxydammar-20(22),24-diene-3-O-β-D-glucopyranosyl(1->2)-β-D-glucopyranoside (186763-78-0,74964-14-0) + 3β-O-[β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-5R,9R,13R-dammarane-20(21),24(25)-diene-12β-ol (494753-69-4)

Guidance literature:

With iron(III) chloride; water; In ethanol; at 40 ℃; for 12h;

DOI:10.1248/cpb.c18-00426

Reference yield:

Ginsenoside Rb1 (41753-43-9,132929-86-3) → 20(R)-ginsenoside Rg3 (38243-03-7) + ginsenoside Rg3 (14197-60-5,38243-03-7,126252-51-5) + ginsenoside Rg5 (186763-78-0,74964-14-0) + 3β-O-[β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-5R,9R,13R-dammarane-20(21),24(25)-diene-12β-ol (494753-69-4)

Guidance literature:

With glycine; at 120 ℃;

DOI:10.1016/j.bmcl.2008.07.056

Reference yield:

20(R)-ginsenoside Rg3 (38243-03-7) → ginsenoside Rg5 (186763-78-0,74964-14-0)

Guidance literature:

20(R)-ginsenoside Rg₃; With pyridine; dmap; acetic anhydride; at 20 ℃; for 10h; Cooling with ice;

With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃; Cooling with ice;

With potassium hydroxide; In 1,4-dioxane; methanol; for 10h; Reflux;

upstream raw materials:

Ginsenoside Rb₁

20(R)-ginsenoside Rg₃

(3β,12β,20R/20S)-12,20-dihydroxydammar-24-en-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

Refernces

• 1、 -. "Blank mixed micelle, and preparation method and applications thereof". Paragraph 0231; 0232; 0233; 0234. . Retrieved 2018/09/08.
• 2、 Lee, Yong Jae,Kim, Hyun Young,Kang, Ki Sung,Lee, Jin Gyun,Yokozawa, Takako,Park, Jeong Hill. "The chemical and hydroxyl radical scavenging activity changes of ginsenoside-Rb1 by heat processing". body text. p. 4515 - 4520. Retrieved 2009/04/08.