Imidazo[2,1-b]quinazolin-2(3H)-one, 1,5-dihydro-7-iodo-

Base Information

Chemical Name:Imidazo[2,1-b]quinazolin-2(3H)-one, 1,5-dihydro-7-iodo-
CAS No.:108857-18-7
Molecular Formula:C10H8IN3O
Molecular Weight:313.098
Hs Code.:2933990090
Mol file:108857-18-7.mol

Synonyms:7-iodo-1,2,3,5-tetrahydro-2-oxoimidazo<2,1-b>quinazoline;

Suppliers and Price of Imidazo[2,1-b]quinazolin-2(3H)-one, 1,5-dihydro-7-iodo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
7-Iodo-3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one 95+%
1g
$ 1568.00

American Custom Chemicals Corporation
7-IODO-3,5-DIHYDROIMIDAZO[2,1-B]QUINAZOLIN-2(1H)-ONE 95.00%
5MG
$ 497.76

Alichem
7-Iodo-3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one
1g
$ 1293.36

Total 3 raw suppliers

Chemical Property of Imidazo[2,1-b]quinazolin-2(3H)-one, 1,5-dihydro-7-iodo-

Chemical Property:

Melting Point:>300 °C
PKA:12.44±0.20(Predicted)
PSA：48.19000
Density:2.18±0.1 g/cm3(Predicted)
LogP:0.87350
Storage Temp.:2-8°C

Purity/Quality:

95%min ^*data from raw suppliers

7-Iodo-3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Imidazo[2,1-b]quinazolin-2(3H)-one, 1,5-dihydro-7-iodo-

There total 10 articles about Imidazo[2,1-b]quinazolin-2(3H)-one, 1,5-dihydro-7-iodo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 116027-13-5
ethyl (2-chloro-6-iodo-3,4-dihydroquinazolin-3-yl)acetate

: 108857-18-7
7-iodo-1,2,3,5-tetrahydroimidazo<2,1-b>quinazolin-2(1H)-one

Guidance literature:: With ammonia; In ethylene glycol; at 0 - 140 ℃;
DOI:10.1021/jm00119a014

Reference yield: 75.0%

: 506-68-3
bromocyane

: 108857-21-2
ethyl N-<(2-amino-5-iodophenyl)methyl>glycinate

: 108857-18-7
7-iodo-1,2,3,5-tetrahydroimidazo<2,1-b>quinazolin-2(1H)-one

Guidance literature:: In ethanol; for 18h; Heating;
DOI:10.1021/jm00129a005

Reference yield:

: 77317-55-6
methyl 2-amino-5-iodobenzoate

: 108857-18-7
7-iodo-1,2,3,5-tetrahydroimidazo<2,1-b>quinazolin-2(1H)-one

Guidance literature:: Multi-step reaction with 6 steps

1: 70 percent / H₂O; acetic acid / Heating

2: 60.5 g / aq. NaOH / methanol / 1 h / Heating

3: 89 percent / POCl₃, N,N-dimethylaniline / 2 h / 150 °C

4: 96 percent / NaBH₄ / CHCl₃; ethanol / 1.) 0 deg C, 2.) room temperature, 1 h

5: 84 percent / potassium carbonate / butan-2-one / Heating

6: 81 percent / NH₃ / ethane-1,2-diol / 0 - 140 °C

With sodium hydroxide; sodium tetrahydroborate; ammonia; potassium carbonate; N,N-dimethyl-aniline; trichlorophosphate; In methanol; ethanol; chloroform; water; ethylene glycol; acetic acid; butanone;
DOI:10.1021/jm00119a014