N2-(2-Methoxyethyl)pyridine-2,3-diamine

Base Information

• Chemical Name: N2-(2-Methoxyethyl)pyridine-2,3-diamine
• CAS No.: 868628-98-2
• Molecular Formula: C₈H₁₃N₃O
• Molecular Weight: 167.211
• Hs Code.: 2933399090
• Mol file: 868628-98-2.mol

Synonyms:Acetamide,2-[(2-hydroxyethyl)amino]-N-[4-(phenylmethoxy)phenyl];N2-(2-hydroxyethyl)-N1-{4-[(phenylmethyl)oxy]phenyl}glycinamide;N2-(2-methoxyethyl)pyridine-2,3-diamine;

Chemical Property of N2-(2-Methoxyethyl)pyridine-2,3-diamine

Chemical Property:

• PSA: 60.17000
• LogP: 1.37630

Purity/Quality:

98%min ^*data from raw suppliers

N2-(2-Methoxyethyl)-2,3-pyridinediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N2-(2-Methoxyethyl)pyridine-2,3-diamine

There total 2 articles about N2-(2-Methoxyethyl)pyridine-2,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxyethylamino-3-nitropyridine (866010-53-9) → N2-(2-methoxyethyl)pyridine-2,3-diamine (868628-98-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 45 ℃; for 6h; under 4500.36 Torr;

DOI:10.3987/COM-05-10447

Reference yield:

2-Chloro-3-nitropyridine (5470-18-8,34515-82-7) → N2-(2-methoxyethyl)pyridine-2,3-diamine (868628-98-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 30.3 g / triethylamine / dioxane / 2 h / Heating

2: 22.34 g / H₂ / Pd/C / ethanol / 6 h / 45 °C / 4500.36 Torr

With hydrogen; triethylamine; palladium on activated charcoal; In 1,4-dioxane; ethanol;

DOI:10.3987/COM-05-10447

Reference yield: 62.0%

N2-(2-methoxyethyl)pyridine-2,3-diamine (868628-98-2) + 3,4-dimethylbenzaldehyde (5973-71-7) → 2-(3,4-dimethylphenyl)-3-(2-methoxyethyl)-3H-imidazo[4,5-b]pyridine

Guidance literature:

In methanol; at 20 ℃;

DOI:10.3987/COM-05-10447

upstream raw materials:

2-methoxyethylamino-3-nitropyridine

2-Chloro-3-nitropyridine

Downstream raw materials:

C₂₃H₃₀N₄O

Refernces