5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one

Base Information

Chemical Name:5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one
CAS No.:177911-57-8
Molecular Formula:C11H23NO2Si
Molecular Weight:229.395
Hs Code.:2933790090
DSSTox Substance ID:DTXSID50437221
Mol file:177911-57-8.mol

Synonyms:177911-57-8;5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one;5-[[tert-butyl(dimethyl)silyl]oxymethyl]pyrrolidin-2-one;5-(((tert-Butyldimethylsilyl)-oxy)methyl)pyrrolidin-2-one;5-((tert-butyldiMethylsilyloxy)Methyl)pyrrolidin-2-one;5-{[(TERT-BUTYLDIMETHYLSILYL)OXY]METHYL}PYRROLIDIN-2-ONE;C11H23NO2Si;SCHEMBL211169;(5R)-5-[[[(tert-Butyl)dimethylsilyl]oxy]methyl]-2-pyrrolidinone;(5S)-5-[[[(tert-Butyl)dimethylsilyl]oxy]methyl]-2-pyrrolidinone;DTXSID50437221;NUPOYZPOLQAMAK-UHFFFAOYSA-N;CHA91157;MFCD10687050;MFCD23135503;AKOS016005026;SS-5179;SY223990;FT-0688569;W11917;A881438;-5Tert-Butyldimethylsilyl)Oxy)Methyl)Pyrrolidin-2-One;5-(((t-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one;(S)-5-[[(tert-Butyldimethylsilyl)oxy]methyl]-2-pyrrolidinone;2-Pyrrolidinone, 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-

Suppliers and Price of 5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one
100mg
$ 75.00

Matrix Scientific
5-(((tert-Butyldimethylsilyl)-oxy)methyl)pyrrolidin-2-one 95+%
1g
$ 227.00

Matrix Scientific
5-(((tert-Butyldimethylsilyl)-oxy)methyl)pyrrolidin-2-one 95+%
5g
$ 672.00

Crysdot
5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one 95+%
1g
$ 446.00

Chemenu
5-(((tert-Butyldimethylsilyl)-oxy)methyl)pyrrolidin-2-one 95%
1g
$ 421.00

American Custom Chemicals Corporation
5-(((TERT-BUTYLDIMETHYLSILYL)OXY)METHYL)PYRROLIDIN-2-ONE 95.00%
1G
$ 445.20

Alichem
5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one
1g
$ 490.50

AK Scientific
5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one
1g
$ 356.00

Total 9 raw suppliers

Chemical Property of 5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one

Chemical Property:

PSA：38.33000
LogP:2.61560
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:229.149805511
Heavy Atom Count:15
Complexity:246

Purity/Quality:

97% ^*data from raw suppliers

5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)OCC1CCC(=O)N1

Technology Process of 5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one

There total 3 articles about 5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 62400-75-3
pyroglutamol

: 177911-57-8
5-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one

Guidance literature:: With 1H-imidazole; In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;

Reference yield:

: 4931-66-2,54571-66-3,64700-65-8
methyl 5-oxopyrrolidine-2-carboxylate

: 177911-57-8
5-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 2 h / 0 - 20 °C / Inert atmosphere

2: 1H-imidazole / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; sodium tetrahydroborate; In methanol; dichloromethane;

Reference yield:

: 149-87-1
Pyroglutamic acid

: 177911-57-8
5-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 2 h / 0 - 20 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 2 h / 0 - 20 °C / Inert atmosphere

3: 1H-imidazole / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; sodium tetrahydroborate; thionyl chloride; In methanol; dichloromethane;