(15R)-Bimatoprost

Base Information

Chemical Name:(15R)-Bimatoprost
CAS No.:1163135-92-9
Molecular Formula:C25H37NO4
Molecular Weight:415.573
Hs Code.:
Mol file:1163135-92-9.mol

Synonyms:15-epi-bimatoprost;19-Hydroxyandrostenedione;4-Androstene-3,17-dione-19-ol;19-Hydroxy-4-androstene-3,17-dione;4-Androsten-19-ol-3,17-dione;19-Hydroxyandrostendione;19-Hydroxy-androst-4-en-3,17-dion;

Suppliers and Price of (15R)-Bimatoprost

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
15(R)-17-phenyl trinor Prostaglandin F2α ethyl amide ≥98%
1mg
$ 122.00

Cayman Chemical
15(R)-17-phenyl trinor Prostaglandin F2α ethyl amide ≥98%
500μg
$ 64.00

Cayman Chemical
15(R)-17-phenyl trinor Prostaglandin F2α ethyl amide ≥98%
10mg
$ 896.00

Cayman Chemical
15(R)-17-phenyl trinor Prostaglandin F2α ethyl amide ≥98%
5mg
$ 512.00

Biosynth Carbosynth
(15R)-Bimatoprost
25 mg
$ 1000.00

Biosynth Carbosynth
(15R)-Bimatoprost
10 mg
$ 650.00

Biosynth Carbosynth
(15R)-Bimatoprost
5 mg
$ 400.00

Biosynth Carbosynth
(15R)-Bimatoprost
2 mg
$ 300.00

Biosynth Carbosynth
(15R)-Bimatoprost
1 mg
$ 200.00

AK Scientific
(15R)-Bimatoprost
5mg
$ 791.00

Total 50 raw suppliers

Chemical Property of (15R)-Bimatoprost

Chemical Property:

Boiling Point:629.8±55.0 °C(Predicted)
PKA:14.25±0.20(Predicted)
PSA：89.79000
Density:1.145±0.06 g/cm3(Predicted)
LogP:3.53780
Storage Temp.:Amber Vial, -20°C Freezer, Under Inert Atmosphere
Solubility.:Chloroform, (Sparingly), Methanol (Sparingly)

Purity/Quality:

> 95% ^*data from raw suppliers

15(R)-17-phenyl trinor Prostaglandin F2α ethyl amide ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An intermediate in the production of Bimatoprost (B386800).

Technology Process of (15R)-Bimatoprost

There total 5 articles about (15R)-Bimatoprost which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.8%

: 1163135-92-9
(5Z)-N-ethyl-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-pentenyl]-cyclopentyl]hept-5-enamide

Guidance literature:: In water; at 20 ℃; for 72h;

Reference yield: 79.0%

: 122675-28-9
methyl ester of 15R-bimatoprost acid

: 75-04-7,85404-22-4
ethylamine

: 1163135-92-9
(5Z)-N-ethyl-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-pentenyl]-cyclopentyl]hept-5-enamide

Guidance literature:: In methanol; water; at 20 ℃; for 72h;

Reference yield: 18.0%

: 1163135-96-3
(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-5-phenylpent-1-en-1-yl]cyc!opentyl}-N-ethylhept-5-enamide

: 1163135-92-9
(5Z)-N-ethyl-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-pentenyl]-cyclopentyl]hept-5-enamide

Guidance literature:: (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-5-phenylpent-1-en-1-yl]cyc!opentyl}-N-ethylhept-5-enamide; With cerium(III) chloride; In methanol; dichloromethane; at -78 ℃; for 0.5h; Inert atmosphere;

With sodium tetrahydroborate; In methanol; dichloromethane; at -78 ℃; for 1h; Inert atmosphere;

With hydrogenchloride; In methanol; dichloromethane; water; pH=3; Inert atmosphere;