Ethyl 4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate

Base Information

Chemical Name:Ethyl 4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate
CAS No.:59944-62-6
Molecular Formula:C6H8N2O3S
Molecular Weight:188.20432
Hs Code.:
DSSTox Substance ID:DTXSID00486103
Wikidata:Q82326126
Mol file:59944-62-6.mol

Synonyms:ETHYL 4-(HYDROXYMETHYL)-1,2,3-THIADIAZOLE-5-CARBOXYLATE;59944-62-6;ethyl 4-(hydroxymethyl)thiadiazole-5-carboxylate;DTXSID00486103;AMY32337;AKOS024463447;A869081;ETHYL4-(HYDROXYMETHYL)-1,2,3-THIADIAZOLE-5-CARBOXYLATE

Suppliers and Price of Ethyl 4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate 95+%
1g
$ 724.00

Alichem
Ethyl4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate
5g
$ 1350.48

Total 8 raw suppliers

Chemical Property of Ethyl 4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate

Chemical Property:

PSA：111.55000
LogP:-0.27140
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:188.02556330
Heavy Atom Count:12
Complexity:167

Purity/Quality:

97% ^*data from raw suppliers

Ethyl4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(N=NS1)CO

Technology Process of Ethyl 4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate

There total 4 articles about Ethyl 4-(hydroxymethyl)-1,2,3-thiadiazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59944-63-7
4-acetoxymethyl-[1,2,3]thiadiazole-5-carboxylic acid ethyl ester

: 59944-62-6
4-hydroxymethyl-[1,2,3]thiadiazole-5-carboxylic acid ethyl ester

Guidance literature:: With sulfuric acid; In ethanol; Ambient temperature;

Reference yield:

: 5982-65-0
N-carboxiamino-hidrazona del acetilacetato de etilo

: 59944-62-6
4-hydroxymethyl-[1,2,3]thiadiazole-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂

2: NBS / CCl₄ / Heating; Irradiation

3: KOAc / Heating

4: H₂SO₄ / ethanol / Ambient temperature

With N-Bromosuccinimide; thionyl chloride; sulfuric acid; potassium acetate; In tetrachloromethane; ethanol;

Reference yield:

: 18212-20-9
4-methyl-1,2,3-thiadiazole-5-carboxylic acid ethyl ester

: 59944-62-6
4-hydroxymethyl-[1,2,3]thiadiazole-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: NBS / CCl₄ / Heating; Irradiation

2: KOAc / Heating

3: H₂SO₄ / ethanol / Ambient temperature

With N-Bromosuccinimide; sulfuric acid; potassium acetate; In tetrachloromethane; ethanol;