(3aS,7aS)-6-Phenethyloctahydro-1H-pyrrolo[2,3-c]pyridine hydrochloride

Base Information

Chemical Name:(3aS,7aS)-6-Phenethyloctahydro-1H-pyrrolo[2,3-c]pyridine hydrochloride
CAS No.:912338-15-9
Molecular Formula:C₁₅H₂₂N₂*ClH
Molecular Weight:266.814
Hs Code.:
DSSTox Substance ID:DTXSID30589939

Synonyms:912338-15-9;(3aS,7aS)-6-Phenethyloctahydro-1H-pyrrolo[2,3-c]pyridine hydrochloride;DTXSID30589939;(3aS,7aS)-6-Phenethyloctahydro-1H-pyrrolo[2,3-c]pyridinehydrochloride;AKOS016006748;DB-327732;(3aS,7aS)-6-(2-Phenylethyl)octahydro-1H-pyrrolo[2,3-c]pyridine--hydrogen chloride (1/1)

Suppliers and Price of (3aS,7aS)-6-Phenethyloctahydro-1H-pyrrolo[2,3-c]pyridine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (3aS,7aS)-6-Phenethyloctahydro-1H-pyrrolo[2,3-c]pyridine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:266.1549764
Heavy Atom Count:18
Complexity:235

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC2C1CCN(C2)CCC3=CC=CC=C3.Cl
Isomeric SMILES:C1CN[C@H]2[C@@H]1CCN(C2)CCC3=CC=CC=C3.Cl

Technology Process of (3aS,7aS)-6-Phenethyloctahydro-1H-pyrrolo[2,3-c]pyridine hydrochloride

There total 5 articles about (3aS,7aS)-6-Phenethyloctahydro-1H-pyrrolo[2,3-c]pyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 912338-20-6
(3aR,7aS)-1-((R)-1-naphthalen-1-ylethyl)-6-phenethyloctahydropyrrolo[2,3-c]pyridine

: 912338-15-9
(3aS,7aS)-6-phenethyloctahydropyrrolo[2,3-c]pyridine hydrochloride

Guidance literature:: With hydrogen; palladium(II) hydroxide/carbon; In methanol; for 16h; under 2585.81 Torr; Parr bottle;

Reference yield:

: 64-04-0
phenethylamine

: 912338-15-9
(3aS,7aS)-6-phenethyloctahydropyrrolo[2,3-c]pyridine hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate / acetonitrile / 15.5 h / 20 - 50 °C / Inert atmosphere

2.1: tetrahydrofuran; dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere; Large scale

3.1: DW-therm / 1.08 h / 240 °C / Inert atmosphere

4.1: diisobutylaluminium hydride / toluene / 2.75 h / -70 - 20 °C / Inert atmosphere

5.1: 10 wt% Pd(OH)2 on carbon; hydrogen / methanol / 16 h / 2585.81 Torr / Inert atmosphere

5.2: 1.67 h / 0 - 27 °C

With 10 wt% Pd(OH)2 on carbon; hydrogen; diisobutylaluminium hydride; potassium carbonate; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile;
DOI:10.1021/op700073g

Reference yield:

: 912338-18-2
C₂₇H₃₀N₂O

: 912338-15-9
(3aS,7aS)-6-phenethyloctahydropyrrolo[2,3-c]pyridine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: DW-therm / 1.08 h / 240 °C / Inert atmosphere

2.1: diisobutylaluminium hydride / toluene / 2.75 h / -70 - 20 °C / Inert atmosphere

3.1: 10 wt% Pd(OH)2 on carbon; hydrogen / methanol / 16 h / 2585.81 Torr / Inert atmosphere

3.2: 1.67 h / 0 - 27 °C

With 10 wt% Pd(OH)2 on carbon; hydrogen; diisobutylaluminium hydride; In methanol; toluene;
DOI:10.1021/op700073g