912338-18-2

Upstream product

• 867324-06-9 N-phenethylbut-3-en-1-amine 
• 64-04-0 phenethylamine 
• 3886-70-2 (R)-1-(1-Naphthyl)ethylamine 

Downstream Products

• 912338-19-3 (3aS,7aS)-1-((R)-1-naphthalen-1-yl-ethyl)-6-phenethyloctahydropyrrolo[2,3-c]pyridin-7-one 
• 912338-15-9 (3aS,7aS)-6-phenethyloctahydropyrrolo[2,3-c]pyridine hydrochloride 
• 912338-20-6 (3aR,7aS)-1-((R)-1-naphthalen-1-ylethyl)-6-phenethyloctahydropyrrolo[2,3-c]pyridine 
• 867324-10-5 (3aS,7aS)-6-phenethyloctahydropyrrolo[2,3-c]pyridine 

Relevant academic research and scientific papers

A facile preparation of an octahydropyrrolo[2,3-c]pyridine enantiomer

A facile synthesis of octahydro-pyrrolo[2,3-c]pyridine 1 using an intramolecular [3+2]-cycloaddition of an azomethine ylide as the key step and employing DW-therm heat-transfer fluid as a solvent is disclosed. Enantiomerically pure 1 was obtained either via a chromatographic separation of the diastereoisomers 12 and 13 resulting from the cycloaddition with a chiral appendage or by a classical resolution of racemate 19.

Organic compounds

Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula I