ethyl 2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate

Base Information

Chemical Name:ethyl 2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate
CAS No.:921940-82-1
Molecular Formula:C₁₄H₂₀N₂O₄
Molecular Weight:280.324
Hs Code.:
Mol file:921940-82-1.mol

Synonyms:Methyl 5-(Boc-amino)pyridine-2-acetate;ethyl 2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate;ethyl 2-[5-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-2-yl]acetate;2-Pyridineacetic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-, ethyl ester

Suppliers and Price of ethyl 2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl5-(Boc-amino)pyridine-2-acetate 95+%
1g
$ 1073.00

Chemenu
Ethyl2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate 95%
1g
$ 667.00

American Custom Chemicals Corporation
ETHYL-2-(5-((TERT-BUTOXYCARBONYL)AMINO)PYRIDIN-2-YL)ACETATE 95.00%
5MG
$ 504.65

Alichem
Ethyl2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate
1g
$ 653.12

AK Scientific
Ethyl2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate
1g
$ 1498.00

Total 10 raw suppliers

Chemical Property of ethyl 2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate

Chemical Property:

Boiling Point:345.2±32.0 °C(Predicted)
PKA:12.71±0.70(Predicted)
PSA：81.01000
Density:1.163±0.06 g/cm3(Predicted)
LogP:2.54780
Storage Temp.:2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl5-(Boc-amino)pyridine-2-acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate

There total 5 articles about ethyl 2-(5-((tert-butoxycarbonyl)amino)pyridin-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 174890-58-5
ethyl 2-(5-aminopyridin-2-yl)acetate

: 24424-99-5
di-tert-butyl dicarbonate

: 921940-82-1
ethyl 2-(5-[[(tert-butoxy)carbonyl]amino]pyridin-2-yl)acetate

Guidance literature:: In 1,4-dioxane; at 18 - 25 ℃; for 18h; Heating / reflux;

Reference yield:

: 4548-45-2
2-chloro-5-nitropyridine

: 921940-82-1
ethyl 2-(5-[[(tert-butoxy)carbonyl]amino]pyridin-2-yl)acetate

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 70 °C

2: sodium chloride; water / dimethyl sulfoxide / 120 °C

3: palladium on activated charcoal; hydrogen / ethanol / 20 °C

4: tetrahydrofuran / 70 °C

With palladium on activated charcoal; water; hydrogen; potassium carbonate; sodium chloride; In tetrahydrofuran; ethanol; dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 174890-57-4
ethyl 2-(5-nitropyridin-2-yl)acetate

: 921940-82-1
ethyl 2-(5-[[(tert-butoxy)carbonyl]amino]pyridin-2-yl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / ethanol / 20 °C

2: tetrahydrofuran / 70 °C

With palladium on activated charcoal; hydrogen; In tetrahydrofuran; ethanol;