Benzyl 4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate

Base Information

Chemical Name:Benzyl 4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate
CAS No.:161610-13-5
Molecular Formula:C18H19FN2O3
Molecular Weight:330.359
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80475873
Wikidata:Q72476839
Mol file:161610-13-5.mol

Synonyms:161610-13-5;benzyl 4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate;2-Fluoro-4/'-hydroxy-3/',4/',5/',6/'-tetrahydro-2/'H[3,4/']bipyridinyl-1/'-carboxylic acid;MQTSRBZFPZJVIG-UHFFFAOYSA-N;SCHEMBL8315488;DTXSID80475873;Benzyl 4-(2-fluoro-3-pyridinyl)-4-hydroxy-1-piperidinecarboxylate;AKOS015941210;2-Fluoro-4'-hydroxy-3',4',5',6'-tetrahydro-2'H[3,4']bipyridinyl-1'-carboxylic acid benzyl ester;1-Benzyloxycarbonyl-4-hydroxy-4-(2-fluoropyrid-3-yl)piperidine;benzyl4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate

Suppliers and Price of Benzyl 4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate 95+%
1g
$ 461.00

Chemenu
benzyl4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate 95%
1g
$ 436.00

American Custom Chemicals Corporation
BENZYL-2-FLUORO-4'-HYDROXY-3',4',5',6'-TETRAHYDRO-2'H[3,4']BIPYRIDINYL-1'-CARBOXYLATE 95.00%
5MG
$ 503.76

Total 5 raw suppliers

Chemical Property of Benzyl 4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate

Chemical Property:

PSA：62.66000
Density:1.306
LogP:2.77880
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:330.13797063
Heavy Atom Count:24
Complexity:421

Purity/Quality:

99% ^*data from raw suppliers

Benzyl4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1(C2=C(N=CC=C2)F)O)C(=O)OCC3=CC=CC=C3

Technology Process of Benzyl 4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate

There total 1 articles about Benzyl 4-(2-fluoropyridin-3-yl)-4-hydroxypiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 372-48-5
2-fluoropyridine

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 161610-13-5
methanoaldehyde

Guidance literature:: 2-fluoropyridine; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; In tetrahydrofuran; hexane; at -78 - -70 ℃; for 1.25h; Inert atmosphere;

benzyl 4-oxo-1-piperidinecarboxylate; In tetrahydrofuran; hexane; at -70 ℃; for 1h; Inert atmosphere;
DOI:10.1021/op0000935