6-Chloro-5-MethylpyriMidine-4-carboxylic acid

Base Information

Chemical Name:6-Chloro-5-MethylpyriMidine-4-carboxylic acid
CAS No.:933702-12-6
Molecular Formula:C6H5ClN2O2
Molecular Weight:172.571
Hs Code.:2933599090
Mol file:933702-12-6.mol

Synonyms:6-chloro-5-methylpyrimidine-4-carboxylicaci;6-Chloro-5-methyl-4-pyrimidinecarboxylic acid;6-Chloro-5-MethylpyriMidine-4-carboxylic acid;4-Pyrimidinecarboxylic acid, 6-chloro-5-methyl-;6-Chloro-5-MethylpyriMidine-4-carboxylic acid ISO 9001：2015 REACH

Suppliers and Price of 6-Chloro-5-MethylpyriMidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Chloro-5-methylpyrimidine-4-carboxylicacid 97%
1g
$ 882.00

Chemenu
6-chloro-5-methylpyrimidine-4-carboxylicacid 97%
1g
$ 832.00

American Custom Chemicals Corporation
6-CHLORO-5-METHYLPYRIMIDINE-4-CARBOXYLIC ACID 95.00%
5MG
$ 504.59

Aaron Chemicals
6-Chloro-5-methylpyrimidine-4-carboxylicacid 97%
5g
$ 745.00

Aaron Chemicals
6-Chloro-5-methylpyrimidine-4-carboxylicacid 97%
250mg
$ 107.00

Total 7 raw suppliers

Chemical Property of 6-Chloro-5-MethylpyriMidine-4-carboxylic acid

Chemical Property:

Boiling Point:342.9±37.0 °C(Predicted)
PKA:1.84±0.37(Predicted)
PSA：63.08000
Density:1.479
LogP:1.13660
Storage Temp.:2-8°C

Purity/Quality:

99% ^*data from raw suppliers

6-Chloro-5-methylpyrimidine-4-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-Chloro-5-MethylpyriMidine-4-carboxylic acid

There total 3 articles about 6-Chloro-5-MethylpyriMidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1232059-52-7
ethyl 6-chloro-5-methyl-pyrimidine-4-carboxylate

: 933702-12-6
C₆H₅ClN₂O₂

Guidance literature:: ethyl 6-chloro-5-methyl-pyrimidine-4-carboxylate; With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 1h;

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 0.166667h;

Reference yield:

: 1159010-94-2
6-hydroxy-5-methyl-pyrimidine-4-carboxylic acid

: 933702-12-6
C₆H₅ClN₂O₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / N,N-dimethyl-formamide / 1 h / Reflux

2.1: potassium carbonate / dichloromethane / 1 h / 0 - 20 °C

3.1: water; lithium hydroxide / tetrahydrofuran / 1 h / 20 °C

3.2: 0.17 h / 20 °C

With thionyl chloride; water; potassium carbonate; lithium hydroxide; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1159010-95-3
6-chloro-5-methyl-pyrimidine-4-carboxylic acid chloride

: 933702-12-6
C₆H₅ClN₂O₂

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / dichloromethane / 1 h / 0 - 20 °C

2.1: water; lithium hydroxide / tetrahydrofuran / 1 h / 20 °C

2.2: 0.17 h / 20 °C

With water; potassium carbonate; lithium hydroxide; In tetrahydrofuran; dichloromethane;