[3-Hydroxy-2-(hydroxymethyl)-6-methoxy-5-methylsulfonyloxyoxan-4-yl] methanesulfonate

Base Information

Chemical Name:[3-Hydroxy-2-(hydroxymethyl)-6-methoxy-5-methylsulfonyloxyoxan-4-yl] methanesulfonate
CAS No.:22860-24-8
Molecular Formula:C9H18 O10 S2
Molecular Weight:350.3632
Hs Code.:
NSC Number:179655
DSSTox Substance ID:DTXSID20306753
Mol file:22860-24-8.mol

Synonyms:NSC179655;22860-24-8;DTXSID20306753;NSC-179655

Suppliers and Price of [3-Hydroxy-2-(hydroxymethyl)-6-methoxy-5-methylsulfonyloxyoxan-4-yl] methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of [3-Hydroxy-2-(hydroxymethyl)-6-methoxy-5-methylsulfonyloxyoxan-4-yl] methanesulfonate

Chemical Property:

Vapor Pressure:2.63E-19mmHg at 25°C
Refractive Index:1.538
Boiling Point:644.1°C at 760 mmHg
Flash Point:343.3°C
Density:1.58g/cm³
XLogP3:-1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:350.03413911
Heavy Atom Count:21
Complexity:530

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1C(C(C(C(O1)CO)O)OS(=O)(=O)C)OS(=O)(=O)C

Technology Process of [3-Hydroxy-2-(hydroxymethyl)-6-methoxy-5-methylsulfonyloxyoxan-4-yl] methanesulfonate

There total 5 articles about [3-Hydroxy-2-(hydroxymethyl)-6-methoxy-5-methylsulfonyloxyoxan-4-yl] methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 65530-21-4
methyl 4,6-O-benzylidene-2,3-di-O-methanesulfonyl-α-D-glucopyranoside

: 22860-24-8
5-hydroxy-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4-diyl-dimethanesulfonate

Guidance literature:: With phosphomolybdic acid; silica gel; In dichloromethane; at 20 ℃; for 5h; chemoselective reaction;
DOI:10.1002/ejoc.200800963

Reference yield: 94.0%

: 98053-23-7
methyl 4,6-O-isopropylidene-2,3-di-O-mesyl-α-D-glucopyranoside

: 22860-24-8
5-hydroxy-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4-diyl-dimethanesulfonate

Guidance literature:: With methanol; acetyl chloride; for 2h;
DOI:10.1016/S0008-6215(00)00009-4

Reference yield:

: 15354-29-7
methyl 4,6-O-isopropylidene-α-D-glucopyranoside

: 22860-24-8
5-hydroxy-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4-diyl-dimethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / CH₂Cl₂ / 24 h / -20 - 20 °C

2: 94 percent / AcCl; MeOH / 2 h

With methanol; acetyl chloride; In dichloromethane; 1: mesylation / 2: Hydrolysis;
DOI:10.1016/S0008-6215(00)00009-4