N4-methylpyridine-3,4-diamine

Base Information

• Chemical Name: N4-methylpyridine-3,4-diamine
• CAS No.: 1839-17-4
• Molecular Formula: C6H9N3
• Molecular Weight: 123.158
• Hs Code.: 2933399090
• European Community (EC) Number: 816-441-4
• DSSTox Substance ID: DTXSID80358692
• Wikidata: Q72439067
• Mol file: 1839-17-4.mol

Synonyms:N4-methylpyridine-3,4-diamine;1839-17-4;4-N-methylpyridine-3,4-diamine;3-amino-4-(methylamino)pyridine;3-Amino-4-(methylamino)-pyridine;3-amino-4-methylaminopyridine;3,4-Pyridinediamine, N4-methyl-;MFCD00982623;4-Methylamino-3-aminopyridine;N4-methylpyridin-3,4-diamine;SCHEMBL2046959;DTXSID80358692;N4-Methyl-pyridine-3,4-diamine;3-Amino-4-(methylamino) pyridine;N~4~-methylpyridine-3,4-diamine;N4-methyl-pyridine-3,4-diyldiamine;STL264113;AKOS005265160;AKOS037645321;SB75545;AS-60125;SY059863;4-(methylimino)-1,4-dihydropyridin-3-amine;CS-0146043;FT-0654577;EN300-93609;C73540;A812824;Z57396117;F1318-0064

Chemical Property of N4-methylpyridine-3,4-diamine

Chemical Property:

• Boiling Point: 317℃
• Flash Point: 146℃
• PSA: 54.17000
• Density: 1.179
• LogP: 0.70860
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 123.079647300
• Heavy Atom Count: 9
• Complexity: 84.4

Purity/Quality:

97% ^*data from raw suppliers

N4-Methylpyridine-3,4-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1=C(C=NC=C1)N

Technology Process of N4-methylpyridine-3,4-diamine

There total 4 articles about N4-methylpyridine-3,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

3-nitro-4-methylaminopyridine (1633-41-6) → 3-amino-4-(methylamino)pyridine (1839-17-4)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 21h;

Reference yield:

4-methoxy-3-nitro-pyridine (31872-62-5) → 3-amino-4-(methylamino)pyridine (1839-17-4)

Guidance literature:

Multi-step reaction with 2 steps

1: methylamine / ethanol; water

2: raney Nickel / methanol

With methylamine; raney Nickel; In methanol; ethanol; water;

Reference yield:

4-chloro-3-nitropyridine (13091-23-1) → 3-amino-4-(methylamino)pyridine (1839-17-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 59 percent / ethanol / 0.33 h / 0 °C

2: H₂ / 5percent Pd/C / ethanol

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1002/jhet.5570270316

upstream raw materials:

3-nitro-4-methylaminopyridine

4-chloro-3-nitropyridine

4-methoxy-3-nitro-pyridine

Downstream raw materials:

1,2-dimethylimidazo<4,5-c>pyridine

2-ethyl-1-methyl-1H-imidazo[4,5-c]pyridine

1-methylimidazo<4,5-c>pyridine

2-(2,4-dimethoxyphenyl)-1-methylimidazo<4,5-c>pyridine dihydrochloride