(3-Bromo-2-fluorophenyl)methanamine

Base Information

Chemical Name:(3-Bromo-2-fluorophenyl)methanamine
CAS No.:261723-28-8
Molecular Formula:C7H7BrFN
Molecular Weight:204.042
Hs Code.:2921490090
European Community (EC) Number:867-497-1
DSSTox Substance ID:DTXSID20949043
Wikidata:Q82926878
Mol file:261723-28-8.mol

Synonyms:(3-bromo-2-fluorophenyl)methanamine;261723-28-8;3-Bromo-2-fluorobenzylamine;MFCD13194194;1-(3-Bromo-2-fluorophenyl)methanamine;Benzenemethanamine, 3-bromo-2-fluoro-;3-Bromo-2-fluoro-benzylamine;SCHEMBL1363756;DTXSID20949043;BAFXXIVSWGQMMI-UHFFFAOYSA-N;AKOS015920367;[(3-Bromo-2-fluorophenyl)methyl]amine;CS-W006679;SB78556;DS-14116;SY112768;FT-0728958;A25550;EN300-864975;N13145;A1-30127

Suppliers and Price of (3-Bromo-2-fluorophenyl)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3-Bromo-2-fluorophenyl)methanamine
50mg
$ 90.00

Crysdot
(3-Bromo-2-fluorophenyl)methanamine 97%
10g
$ 1225.00

Crysdot
(3-Bromo-2-fluorophenyl)methanamine 97%
25g
$ 2200.00

Crysdot
(3-Bromo-2-fluorophenyl)methanamine 97%
5g
$ 850.00

Crysdot
(3-Bromo-2-fluorophenyl)methanamine 97%
1g
$ 360.00

Crysdot
(3-Bromo-2-fluorophenyl)methanamine 97%
250mg
$ 144.00

Chemenu
(3-bromo-2-fluorophenyl)methanamine 95+%
1g
$ 337.00

Chemcia Scientific
3-Bromo-2-fluoro-benzylamine 95%
1 G
$ 350.00

Apolloscientific
(3-Bromo-2-fluorophenyl)methanamine 97%
1g
$ 493.00

Apolloscientific
(3-Bromo-2-fluorophenyl)methanamine 97%
100mg
$ 124.00

Total 27 raw suppliers

Chemical Property of (3-Bromo-2-fluorophenyl)methanamine

Chemical Property:

Boiling Point:245.2±25.0 °C(Predicted)
PKA:8.35±0.10(Predicted)
PSA：26.02000
Density:1.571±0.06 g/cm3(Predicted)
LogP:2.74720
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:202.97459
Heavy Atom Count:10
Complexity:110

Purity/Quality:

97% ^*data from raw suppliers

(3-Bromo-2-fluorophenyl)methanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)Br)F)CN

Technology Process of (3-Bromo-2-fluorophenyl)methanamine

There total 7 articles about (3-Bromo-2-fluorophenyl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 871353-25-2
3-bromo-2-fluorophenylamide

: 261723-28-8
(3-bromo-2-fluorophenyl)methanamine

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; at 50 ℃; for 2h;

Reference yield:

: C₇H₅BrFN₃

: 261723-28-8
(3-bromo-2-fluorophenyl)methanamine

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; water; at 50 ℃; for 12h; Inert atmosphere;

Reference yield:

3-bromo-2-fluorobenzoic acid: 161957-56-8
3-bromo-2-fluorobenzoic acid

: 261723-28-8
(3-bromo-2-fluorophenyl)methanamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / dichloromethane / 6 h / Reflux

2.1: ammonium hydroxide / ethyl acetate

3.1: dimethylsulfide borane complex / tetrahydrofuran / 2 h / 50 °C

3.2: 2 h

3.3: pH 9

With ammonium hydroxide; thionyl chloride; dimethylsulfide borane complex; In tetrahydrofuran; dichloromethane; ethyl acetate;