DIBUTYL 2,2'-BIPYRIDINE-4,4'-DICARBOXYLATE

Base Information

• Chemical Name: DIBUTYL 2,2'-BIPYRIDINE-4,4'-DICARBOXYLATE
• CAS No.: 69641-93-6
• Molecular Formula: C₂₀H₂₄N₂O₄
• Molecular Weight: 356.422
• Mol file: 69641-93-6.mol

Synonyms:DIBUTYL 2,2-BIPYRIDINE-4,4-DICARBOXYLATE;4,4-di-tert-butyl bipyridine(dtbpy)

Chemical Property of DIBUTYL 2,2'-BIPYRIDINE-4,4'-DICARBOXYLATE

Chemical Property:

• Melting Point: 108-110 °C(Solv: acetone (67-64-1))
• Boiling Point: 503.3±50.0 °C(Predicted)
• PKA: 1.88±0.30(Predicted)
• PSA: 78.38000
• Density: 1.127±0.06 g/cm3(Predicted)
• LogP: 4.05740
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

DIBUTYL-2,2'-BIPYRIDINE-4,4'-DICARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIBUTYL 2,2'-BIPYRIDINE-4,4'-DICARBOXYLATE

There total 5 articles about DIBUTYL 2,2'-BIPYRIDINE-4,4'-DICARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

→ 4,4'-bis(butoxycarbonyl)-2,2'-bipyridine (69641-93-6)

Guidance literature:

With sulfuric acid; for 24h; Reflux;

With sodium hydroxide; In water; at 0 ℃;

Reference yield:

4,4'-dibromo-2,2'-bipyridine (18511-71-2) + carbon monoxide (201230-82-2) + butan-1-ol (71-36-3) → 4,4'-bis(butoxycarbonyl)-2,2'-bipyridine (69641-93-6)

Guidance literature:

With tributyl-amine; bis-triphenylphosphine-palladium(II) chloride; under 760.051 Torr; Heating;

DOI:10.1021/jo000635g

Reference yield:

2,2'-Bipyridine-4,4'-dicarboxylic acid (6813-38-3) → 4,4'-bis(butoxycarbonyl)-2,2'-bipyridine (69641-93-6)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine; oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 6 h / Inert atmosphere

2: 12 h / Reflux; Inert atmosphere

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;

DOI:10.1021/acs.inorgchem.5b01328

upstream raw materials:

4,4'-dibromo-2,2'-bipyridine

carbon monoxide

butan-1-ol

2,2'-bipyridyl-4,4'-dicarboxylic acid chloride