BOC-4-(4-BROMOPHENYL)-PIPERIDINE-4-CARBOXYLIC ACID

Base Information

Chemical Name:BOC-4-(4-BROMOPHENYL)-PIPERIDINE-4-CARBOXYLIC ACID
CAS No.:1076197-05-1
Molecular Formula:C17H22BrNO4
Molecular Weight:384.27
Hs Code.:2933399090
Mol file:1076197-05-1.mol

Synonyms:1-BOC-4-(4-BROMOPHENYL)-4-PIPERIDINEDICARBOXYLIC ACID;BOC-4-(4-BROMOPHENYL)-PIPERIDINE-4-CARBOXYLIC ACID;4-(4-Bromo-phenyl)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester;4-(4-BroMophenyl)-1-BOC-piperidin-4-carboxylic acid

Suppliers and Price of BOC-4-(4-BROMOPHENYL)-PIPERIDINE-4-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylicAcid
100mg
$ 90.00

TRC
4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylicAcid
50mg
$ 45.00

Matrix Scientific
4-(4-Bromophenyl)-1-tert-butoxycarbonyl-piperidine-4-carboxylic acid >95%
5g
$ 925.00

Matrix Scientific
4-(4-Bromophenyl)-1-tert-butoxycarbonyl-piperidine-4-carboxylic acid >95%
1g
$ 230.00

Apolloscientific
1-Boc-4-(4-bromophenyl)-4-carboxypiperidine 97%
1g
$ 283.00

Apolloscientific
1-Boc-4-(4-bromophenyl)-4-carboxypiperidine 97%
500mg
$ 221.00

Apolloscientific
1-Boc-4-(4-bromophenyl)-4-carboxypiperidine 97%
250mg
$ 138.00

American Custom Chemicals Corporation
4-(4-BROMOPHENYL)-1-(TERT-BUTOXYCARBONYL)PIPERIDINE-4-CARBOXYLIC ACID 95.00%
5MG
$ 501.18

Alichem
1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylicacid
1g
$ 1668.15

Alichem
1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylicacid
500mg
$ 1019.20

Total 16 raw suppliers

Chemical Property of BOC-4-(4-BROMOPHENYL)-PIPERIDINE-4-CARBOXYLIC ACID

Chemical Property:

Boiling Point:484.4±45.0 °C(Predicted)
PKA:3.96±0.20(Predicted)
PSA：66.84000
Density:1.393±0.06 g/cm3(Predicted)
LogP:3.74030

Purity/Quality:

97% ^*data from raw suppliers

4-(4-Bromophenyl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of BOC-4-(4-BROMOPHENYL)-PIPERIDINE-4-CARBOXYLIC ACID

There total 4 articles about BOC-4-(4-BROMOPHENYL)-PIPERIDINE-4-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 847615-14-9
tert-butyl 4-(4-bromophenyl)-4-cyano-piperidine-1-carboxylate

: 1076197-05-1
4-(4-bromophenyl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; water; at 60 ℃; for 48h;
DOI:10.1039/c8md00197a

Reference yield: 68.0%

: 1076197-05-1
4-(4-bromophenyl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; for 48h; Reflux;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1076197-05-1
4-(4-bromophenyl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / dichloromethane / 0.17 h / 0 °C

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 17 h / 0 - 60 °C

3: sodium hydroxide; water / ethanol / 48 h / Reflux

With water; sodium hydride; sodium hydroxide; In ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.ejmech.2017.06.067