847615-14-9

Basic information

• Product Name: TERT-BUTYL 4-(4-BROMOPHENYL)-4-CYANOPIPERIDINE-1-CARBOXYLATE
• Synonyms: TERT-BUTYL 4-(4-BROMOPHENYL)-4-CYANOPIPERIDINE-1-CARBOXYLATE;5'-bromo-2',4-difluoro-[1,1'-biphenyl]-2-carbonitrile;1-Piperidinecarboxylic acid, 4-(4-broMophenyl)-4-cyano-,1,1-diMethylethyl ester;4-(4-Bromophenyl)-4-cyanopiperidine-1-carboxylic acid tert-butyl ester;1-Boc-4-cyano-4-(4-broMophenyl)-piperidine;tert-Butyl 4-(4-bromophenyl)-4-cyano-1-piperidinecarboxylate
• CAS NO: 847615-14-9
• Molecular Formula: C₁₇H₂₁BrN₂O₂
• Molecular Weight: 365.28
• Mol File: 847615-14-9.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Density: 1.35
• CAS DataBase Reference: TERT-BUTYL 4-(4-BROMOPHENYL)-4-CYANOPIPERIDINE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 4-(4-BROMOPHENYL)-4-CYANOPIPERIDINE-1-CARBOXYLATE(847615-14-9)
• EPA Substance Registry System: TERT-BUTYL 4-(4-BROMOPHENYL)-4-CYANOPIPERIDINE-1-CARBOXYLATE(847615-14-9)

Safety Data

• Hazardous Substances Data: 847615-14-9(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-(4-bromophenyl)-4-cyanopiperidine-1-carboxylate is a chemical compound with a molecular formula C19H24BrN3O2. It is a piperidine derivative with a tert-butyl ester group and a 4-(4-bromophenyl)-4-cyanopiperidine-1-carboxylate moiety. This chemical is commonly used in the synthesis of pharmaceutical compounds as a building block. It has potential applications in medicinal chemistry and drug discovery due to its unique structural features and biological activities. The compound may have potential therapeutic properties, although further research and testing are needed to fully understand its potential uses and effects.

Upstream product

• 16532-79-9 4-Bromophenylacetonitrile 
• 401518-11-4 [(tert-butoxycarbonyl)imino]diethane-2,1-diyl dimethanesulfonate 
• 118753-70-1 N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1255666-69-3 4-(4-bromophenyl)piperidine-4-carbonitrile 
• 1076197-05-1 4-(4-bromophenyl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid 
• 917899-11-7 4-[4-(1-dimethylsulphamoyl-3-methyl-1H-pyrazol-4-yl)-phenyl]-4-(3-methoxy-phenoxymethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 917899-07-1 4-(4-bromo-phenyl)-4-hydroxymethyl-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 
• 917899-08-2 4-bromomethyl-4-(4-bromo-phenyl)-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 
• 917899-12-8 4-(3-methoxy-phenoxymethyl)-4-[4-(3-methyl-1H-pyrazol-4-yl)-phenyl]-piperidine 
• 917899-09-3 4-(4-bromo-phenyl)-4-(3-methoxy-phenoxymethyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

AZAINDOLE DERIVATIVE AND USE THEREOF AS FGFR AND C-MET INHIBITOR

A series of pyrazolopymidine derivatives, and use thereof in the preparation of a medicament for treating disease associated with FGFR and c-Met. The pyrazolopymidine derivative is a compound represented by formula (I), a tautomer, or a pharmaceutically acceptable salt thereof.

A nitrogen-containing heterocyclic phenyl piperidine compound and its preparation method and application

The invention discloses a nitrogen-containing heterocyclic phenyl piperidine compound or pharmaceutical salt thereof. The general structural formula a of the compound is as shown in specification, wherein R represents hydrogen, mono-substituted or poly-substituted halogen, methyl, methoxyl, tertiary butyl or trifluoromethyl; and R2 is hydrogen, chlorine, bromine, methyl or ethyl. The compound disclosed by the invention is novel in structure; and by introducing the active amino in the form of a piperidine ring, the configuration of the side-chain amino is reinforced and the rigidity of the compound is enhanced. Through the design transformation, the Akt1 kinase inhibitory activity and the PC-3 cell line growth inhibitory activity of the compound are significantly enhanced.

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.