7-Amino-4-bromoisoindolin-1-one

Base Information

Chemical Name:7-Amino-4-bromoisoindolin-1-one
CAS No.:169045-01-6
Molecular Formula:C8H7BrN2O
Molecular Weight:227.06
Hs Code.:2933790090
European Community (EC) Number:959-312-9
DSSTox Substance ID:DTXSID50599313
Wikidata:Q82495188
Mol file:169045-01-6.mol

Synonyms:7-amino-4-bromoisoindolin-1-one;169045-01-6;7-AMINO-4-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE;7-AMINO-4-BROMO-2,3-DIHYDROISOINDOL-1-ONE;7-AMINO-4-BROMO-2,3-DIHYDRO-1H-ISOINDOL-1-ONE;MFCD11215515;1H-Isoindol-1-one, 7-amino-4-bromo-2,3-dihydro-;7-amino-4-bromoisoindolinone;SCHEMBL3041897;DTXSID50599313;CZZMFBYDHNKOMT-UHFFFAOYSA-N;7-amino-4-bromo-isoindolin-1-one;AKOS024260377;AB63856;SB34181;PS-19912;SY290336;DB-264036;CS-0107286;D76723;EN300-1590473;1h-isoindol-1-one,7-amino-4-bromo-2,3-dihydro-;A929665;Z1269134505

Suppliers and Price of 7-Amino-4-bromoisoindolin-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Amino-4-bromo-2,3-dihydroisoindol-1-one
10mg
$ 45.00

TRC
7-Amino-4-bromo-2,3-dihydroisoindol-1-one
100mg
$ 260.00

J&W Pharmlab
7-Amino-4-bromo-2,3-dihydro-isoindol-1-one 96%
50mg
$ 131.00

Crysdot
7-Amino-4-bromoisoindolin-1-one 95+%
1g
$ 581.00

Chemenu
7-Amino-4-bromo-2,3-dihydro-isoindol-1-one 95%
1g
$ 549.00

Chemcia Scientific
7-Amino-4-bromo-2,3-dihydro-isoindol-1-one 95%
0.5 G
$ 395.00

Alichem
7-Amino-4-bromoisoindolin-1-one
25g
$ 7035.00

Alichem
7-Amino-4-bromoisoindolin-1-one
10g
$ 4100.40

Alichem
7-Amino-4-bromoisoindolin-1-one
5g
$ 2680.00

AK Scientific
7-Amino-4-bromoisoindolin-1-one
2.5g
$ 2018.00

Total 8 raw suppliers

Chemical Property of 7-Amino-4-bromoisoindolin-1-one

Chemical Property:

Melting Point:>190oC (dec.)
Boiling Point:524.6±50.0 °C(Predicted)
PKA:13.56±0.20(Predicted)
PSA：58.61000
Density:1.753±0.06 g/cm3(Predicted)
LogP:1.86630
Storage Temp.:Refrigerator, under inert atmosphere
Solubility.:DMSO (Slightly, Sonicated), Tetrahydrofuran (Very Slightly)
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:225.97418
Heavy Atom Count:12
Complexity:209

Purity/Quality:

98%+ ^*data from raw suppliers

7-Amino-4-bromo-2,3-dihydroisoindol-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(C=CC(=C2C(=O)N1)N)Br

Technology Process of 7-Amino-4-bromoisoindolin-1-one

There total 9 articles about 7-Amino-4-bromoisoindolin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 866767-11-5
7-amino-4-bromo-3-hydroxyisoindolinone

: 169045-01-6
7-amino-4-bromoisoindolin-1-one

Guidance literature:: With triethylsilane; trifluoroacetic acid; In nitromethane; at 20 ℃; for 2h;

Reference yield:

: 99548-54-6
methyl 3-bromo-2-methylbenzoate

: 169045-01-6
7-amino-4-bromoisoindolin-1-one

Guidance literature:: Multi-step reaction with 4 steps

1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3.5 h / Reflux; Inert atmosphere

2: ammonium hydroxide / tetrahydrofuran / 20 °C / Inert atmosphere

3: nitric acid; sulfuric acid / 0 - 20 °C

4: iron; hydrogenchloride / ethanol; water / 1 h / Inert atmosphere; Reflux

With hydrogenchloride; ammonium hydroxide; N-Bromosuccinimide; sulfuric acid; nitric acid; iron; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; ethanol; water;