2-METHYLVALERIC ACID

Base Information

• Chemical Name: 2-METHYLVALERIC ACID
• CAS No.: 22160-39-0
• Molecular Formula: C6H12O2
• Molecular Weight: 116.15800
• Mol file: 22160-39-0.mol

Synonyms:methylpentanoic acid;2-methyl pentanoic acid;acidemethylvalerique;2-Methyl-valeric acid;Pentanoic acid, 2-methyl-, (±)-;methylvaleric acid;2-methylpentanoic;

Chemical Property of 2-METHYLVALERIC ACID

Chemical Property:

• Melting Point: -85°C
• Refractive Index: n20/D 1.414(lit.)
• Boiling Point: 196-197oC(lit.)
• Flash Point: 196 °F
• PSA: 37.30000
• Density: 0.931 g/mL at 25oC(lit.)
• LogP: 1.50720

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYLVALERIC ACID

There total 76 articles about 2-METHYLVALERIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Ru((-)-BINAP)(O2 CCH3)2 + 2-methylpent-2-enoic acid (16957-70-3) + argon → 2-Methylpentanoic acid (97-61-0,22160-39-0)

Guidance literature:

In methanol;

Reference yield: 99.0%

2-methylvaleraldehyde (123-15-9) → 2-Methylpentanoic acid (97-61-0,22160-39-0)

Guidance literature:

With C₄H₁₁FeMo₆NO₂₄^(3-)*3C₁₆H₃₆N⁽¹⁺⁾; water; oxygen; sodium carbonate; at 50 ℃; for 8h; under 760.051 Torr; Green chemistry;

DOI:10.1002/anie.201612225

Reference yield: 95.3%

sodium 2-methylpentanoate (17265-25-7) → 2-Methylpentanoic acid (97-61-0,22160-39-0)

Guidance literature:

With hydrogenchloride; In water; at 10 - 25 ℃; for 1h;

upstream raw materials:

2-methylpentan-1-ol

2-C-hydroxymethyl-D-ribonic acid

2-methyl-2-propyl-1,3-propanediol

2-methylvaleraldehyde

Downstream raw materials:

manzanate

benzyl 2-methylpentanoate

2-Methylpentansaeure-cyclohexylester

methyl (R)-2-methylbutyric acid

Refernces

• 1、 Dühren, Ricarda,Kucmierczyk, Peter,Jackstell, Ralf,Franke, Robert,Beller, Matthias. "Ruthenium-catalysed hydroxycarbonylation of olefins". . p. 2026 - 2030. Retrieved 2021/04/09.
• 2、 Takamatsu, Keigo,Kasai, Miku,Nishizawa, Hinaru,Suzuki, Rio,Konno, Hiroyuki. "Aerobic oxidation of aldehydes to acids with N-hydroxyphthalimide derivatives". . . Retrieved 2021/09/14.