TERT-BUTYL 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)PIPERIDINE-1-CARBOXYLATE

Base Information

Chemical Name:TERT-BUTYL 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)PIPERIDINE-1-CARBOXYLATE
CAS No.:301221-19-2
Molecular Formula:C17H23N3O2
Molecular Weight:301.38300
Hs Code.:
Mol file:301221-19-2.mol

Synonyms:1-(t-Butoxycarbonyl)4-(imidazo[1,2-a]pyridin-3-yl)piperidine;1-(t-butoxycarbonyl)-4-(imidazo[1,2-a]pyridin-3-yl)-piperidine;Tert-butyl 4-(imidazo[1,2-a]pyridine-3-yl)piperidine-1-carboxylate;4-Imidazo[1,2-a]pyridin-3-yl-piperidine-1-carboxylic acid tert-butyl ester;tert-butyl 4-(Imidazo[1,2-a]pyridin-3-yl)piperidine-1-carboxylate;

Suppliers and Price of TERT-BUTYL 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)PIPERIDINE-1-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of TERT-BUTYL 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)PIPERIDINE-1-CARBOXYLATE

Chemical Property:

PSA：46.84000
LogP:3.38670

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of TERT-BUTYL 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)PIPERIDINE-1-CARBOXYLATE

There total 8 articles about TERT-BUTYL 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)PIPERIDINE-1-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 301221-63-6
tert-butyl 4-(1-bromo-2-oxoethyl)piperidine-1-carboxylate

: 504-29-0
2-aminopyridine

: 301221-19-2
tert-butyl 4-(imidazo[1,2-a]pyridin-3-yl)piperidine-1-carboxylate

Guidance literature:: In ethanol; for 3h; Reflux;
DOI:10.1021/jm701548u

Reference yield:

: 89151-44-0
4-(2-hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester

: 301221-19-2
tert-butyl 4-(imidazo[1,2-a]pyridin-3-yl)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 50 percent / C₆H₅N(CH₃)3Br*Br₂ / tetrahydrofuran / 0.75 h / 0 °C

2: ethanol / Heating

With phenyltrimethylammonium tribromide; In tetrahydrofuran; ethanol; 1: Swern oxidation;
DOI:10.1016/j.bmcl.2005.02.030

Reference yield:

: 142374-19-4
tert-butyl 4-(formylmethyl)piperidine-1-carboxylate

: 301221-19-2
tert-butyl 4-(imidazo[1,2-a]pyridin-3-yl)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / C₆H₅N(CH₃)3Br*Br₂ / tetrahydrofuran / 0.75 h / 0 °C

2: ethanol / Heating

With phenyltrimethylammonium tribromide; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmcl.2005.02.030