2-(p-Chlorophenyl)-2-ethyl-1,3-propanediol

Base Information

Chemical Name:2-(p-Chlorophenyl)-2-ethyl-1,3-propanediol
CAS No.:25451-05-2
Molecular Formula:C₁₁H₁₅ClO₂
Molecular Weight:214.692
Hs Code.:
DSSTox Substance ID:DTXSID00948332
Nikkaji Number:J50.786E
Wikidata:Q82926146
Mol file:25451-05-2.mol

Synonyms:25451-05-2;2-(p-Chlorophenyl)-2-ethyl-1,3-propanediol;2-(4-chlorophenyl)-2-ethylpropane-1,3-diol;1,3-Propanediol, 2-(p-chlorophenyl)-2-ethyl-;DTXSID00948332;AKOS018005695

Suppliers and Price of 2-(p-Chlorophenyl)-2-ethyl-1,3-propanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(p-Chlorophenyl)-2-ethyl-1,3-propanediol

Chemical Property:

Vapor Pressure:6.39E-06mmHg at 25°C
Boiling Point:363.5°C at 760 mmHg
PKA:14.05±0.10(Predicted)
Flash Point:173.6°C
PSA：40.46000
Density:1.195g/cm³
LogP:1.97240
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:214.0760574
Heavy Atom Count:14
Complexity:161

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(CO)(CO)C1=CC=C(C=C1)Cl

Technology Process of 2-(p-Chlorophenyl)-2-ethyl-1,3-propanediol

There total 1 articles about 2-(p-Chlorophenyl)-2-ethyl-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 78158-65-3
4-chloro-α-ethyl-benzeneacetaldehyde

: 25451-05-2
2-(4-Chloro-phenyl)-2-ethyl-propane-1,3-diol

Guidance literature:: DOI:10.1021/jm00303a029

Reference yield:

: 25451-05-2
2-(4-Chloro-phenyl)-2-ethyl-propane-1,3-diol

: 407-25-0
trifluoroacetic anhydride

: 476158-84-6
(Z)-4-(4-Chloro-phenyl)-1,1,1-trifluoro-4-methoxy-3-methyl-but-3-en-2-one

Guidance literature:: With pyridine; In chloroform; at 0 - 60 ℃;
DOI:10.1016/S0022-1139(02)00287-7

Reference yield:

: 25451-05-2
2-(4-Chloro-phenyl)-2-ethyl-propane-1,3-diol

: 6-(4-chloro-phenyl)-5-methyl-4-trifluoromethyl-1H-pyrimidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / CHCl₃ / 0 - 60 °C

2: 23 percent / aq. HCl / methanol / 72 h / 60 - 65 °C

With pyridine; hydrogenchloride; In methanol; chloroform;
DOI:10.1016/S0022-1139(02)00287-7