1H-INDAZOLE-5-CARBOHYDRAZIDE

Base Information

• Chemical Name: 1H-INDAZOLE-5-CARBOHYDRAZIDE
• CAS No.: 1005205-25-3
• Molecular Formula: C8H8N4O
• Molecular Weight: 176.178
• Hs Code.: 2933990090
• Mol file: 1005205-25-3.mol

Synonyms:1H-INDAZOLE-5-CARBOXYLIC ACID HYDRAZIDE;

Chemical Property of 1H-INDAZOLE-5-CARBOHYDRAZIDE

Chemical Property:

• PSA: 83.80000
• LogP: 1.25760

Purity/Quality:

97% ^*data from raw suppliers

1H-Indazole-5-carbohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-INDAZOLE-5-CARBOHYDRAZIDE

There total 6 articles about 1H-INDAZOLE-5-CARBOHYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl 1H-indazole-5-carboxylate (473416-12-5) → 1H-indazole-5-carbohydrazide (1005205-25-3)

Guidance literature:

With hydrazine hydrate; In ethanol; at 80 ℃; for 5h;

Reference yield: 95.0%

1H-indazole-5-carboxylic acid ethyl ester (192944-51-7) → 1H-indazole-5-carbohydrazide (1005205-25-3)

Guidance literature:

With hydrazine hydrate monohydrate; In methanol; at 140 ℃; for 1h; Microwave irradiation; Sealed tube;

DOI:10.1016/j.ejmech.2015.06.028

Reference yield:

C9H5Cl3N2O → 1H-indazole-5-carbohydrazide (1005205-25-3)

Guidance literature:

With hydrazine; In methanol; at 60 ℃;

DOI:10.1016/j.bmcl.2013.09.055

upstream raw materials:

methyl 1H-indazole-5-carboxylate

benzimidazole

1H-indazole-5-carboxylic acid ethyl ester

1H-indazole-5-carboxylic acid

Downstream raw materials:

C₁₆H₁₃N₅O

N'-[3-[3-(trifluoromethyl)phenyl]propionyl]-1H-indazole-5-carbohydrazide

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