N,N-diethyl-2-[4-[(Z)-1-(4-fluorophenyl)-2-phenylethenyl]phenoxy]ethanamine

Base Information

Chemical Name:N,N-diethyl-2-[4-[(Z)-1-(4-fluorophenyl)-2-phenylethenyl]phenoxy]ethanamine
CAS No.:110465-94-6
Molecular Formula:C26H28 F N O
Molecular Weight:389.51
Hs Code.:2922299090
Mol file:110465-94-6.mol

Synonyms:1-(4-fluorophenyl)-1-(4-(2-N,N-diethylamino)ethoxy)phenyl-2-phenylethylene;1-FDEPCP;fluoro-clomiphene

Suppliers and Price of N,N-diethyl-2-[4-[(Z)-1-(4-fluorophenyl)-2-phenylethenyl]phenoxy]ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N,N-diethyl-2-[4-[(Z)-1-(4-fluorophenyl)-2-phenylethenyl]phenoxy]ethanamine

Chemical Property:

Vapor Pressure:1.44E-09mmHg at 25°C
Boiling Point:485.2°C at 760 mmHg
Flash Point:247.2°C
PSA：12.47000
Density:1.09g/cm³
LogP:6.13520
XLogP3:6.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:9
Exact Mass:389.21549268
Heavy Atom Count:29
Complexity:467

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCOC1=CC=C(C=C1)C(=CC2=CC=CC=C2)C3=CC=C(C=C3)F
Isomeric SMILES:CCN(CC)CCOC1=CC=C(C=C1)/C(=C/C2=CC=CC=C2)/C3=CC=C(C=C3)F

Technology Process of N,N-diethyl-2-[4-[(Z)-1-(4-fluorophenyl)-2-phenylethenyl]phenoxy]ethanamine

There total 4 articles about N,N-diethyl-2-[4-[(Z)-1-(4-fluorophenyl)-2-phenylethenyl]phenoxy]ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 869-24-9
2-chloro-N,N-diethylethylamine hydrochloride

: 110465-93-5
1-(4-fluorophenyl)-1-(4-hydroxyphenyl)-2-phenylethylene

: 110465-94-6
1-(4-fluorophenyl)-1-<4-<2-(N,N-diethylamino)ethoxy>phenyl>-2-phenylethylene

Guidance literature:: With potassium hydroxide; In ethanol; for 3h; Heating;
DOI:10.1016/0039-128X(86)90042-5

Reference yield:

: 345-89-1
4-fluoro-4'-methoxybenzophenone

: 110465-94-6
1-(4-fluorophenyl)-1-<4-<2-(N,N-diethylamino)ethoxy>phenyl>-2-phenylethylene

Guidance literature:: Multi-step reaction with 3 steps

1: 2) AcOH, H₂SO₄ / 1) ether, reflux, 5 h, 2) r.t., 3 h

2: 92 percent / BBr₃ / CH₂Cl₂ / 1 h / Ambient temperature

3: 69 percent / KOH / ethanol / 3 h / Heating

With potassium hydroxide; sulfuric acid; boron tribromide; acetic acid; In ethanol; dichloromethane;
DOI:10.1016/0039-128X(86)90042-5

Reference yield:

: 110485-90-0
1-(4-fluorophenyl)-1-(4-methoxyphenyl)-2-phenylethylene

: 110465-94-6
1-(4-fluorophenyl)-1-<4-<2-(N,N-diethylamino)ethoxy>phenyl>-2-phenylethylene

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / BBr₃ / CH₂Cl₂ / 1 h / Ambient temperature

2: 69 percent / KOH / ethanol / 3 h / Heating

With potassium hydroxide; boron tribromide; In ethanol; dichloromethane;
DOI:10.1016/0039-128X(86)90042-5