(Bicyclo(2.2.1)hept-2-ylidene)acetamide

Base Information

• Chemical Name: (Bicyclo(2.2.1)hept-2-ylidene)acetamide
• CAS No.: 80106-53-2
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.208
• Mol file: 80106-53-2.mol

Synonyms:(bicyclo(2.2.1)hept-2-ylidene)acetamide;(bicyclo(2.2.1)hept-2-ylidene)acetic acid amide;BCHYE-AC

Chemical Property of (Bicyclo(2.2.1)hept-2-ylidene)acetamide

Chemical Property:

• Vapor Pressure: 0.000111mmHg at 25°C
• Boiling Point: 336.7°C at 760 mmHg
• Flash Point: 157.4°C
• Density: 1.227g/cm³
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 151.099714038
• Heavy Atom Count: 11
• Complexity: 220

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC2CC1CC2=CC(=O)N
• Isomeric SMILES: C1CC\2CC1C/C2=C\C(=O)N

Technology Process of (Bicyclo(2.2.1)hept-2-ylidene)acetamide

There total 2 articles about (Bicyclo(2.2.1)hept-2-ylidene)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(bicyclo<2.2.1>hept-2-ylidene)acetonitrile → (bicyclo<2.2.1>hept-2-ylidene)acetic acid amide (80106-53-2)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In ethanol; water; 1.) 45-50 deg C, 2 h; 2.) 3 h, r.t.;

Reference yield:

2-norbornanone (497-38-1,2630-41-3,22270-13-9,29583-35-5) → (bicyclo<2.2.1>hept-2-ylidene)acetic acid amide (80106-53-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / 85percent KOH / 24 h / Heating

2: 60 percent / 25percent NaOH, 36percent hydrogen peroxide / ethanol; H₂O / 1.) 45-50 deg C, 2 h; 2.) 3 h, r.t.

With potassium hydroxide; sodium hydroxide; dihydrogen peroxide; In ethanol; water;

upstream raw materials:

2-norbornanone

Refernces