7-BroMo-1H-pyrazolo[4,3-c...

Base Information

• Chemical Name: 7-BroMo-1H-pyrazolo[4,3-c...
• CAS No.: 1256821-58-5
• Molecular Formula: C6H4BrN3
• Molecular Weight: 198.02000
• Mol file: 1256821-58-5.mol

Synonyms:7-bromo-1H-pyrazolo[4,3-c]pyridine;

Chemical Property of 7-BroMo-1H-pyrazolo[4,3-c...

Chemical Property:

• Boiling Point: 357.5±22.0 °C(Predicted)
• PKA: 9.46±0.40(Predicted)
• PSA: 41.57000
• Density: 1.894±0.06 g/cm3(Predicted)
• LogP: 1.72040
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

7-Bromo-1H-pyrazolo[4,3-c]pyridine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-BroMo-1H-pyrazolo[4,3-c...

There total 5 articles about 7-BroMo-1H-pyrazolo[4,3-c... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5-bromo-4-chloro-pyridine-3-carbaldehyde (1060802-24-5) → 7-bromo-1H-pyrazolo[4,3-c]pyridine (1256821-58-5)

Guidance literature:

With hydrazine hydrate; In dimethyl sulfoxide; at 130 - 140 ℃; for 16h;

Reference yield:

3-bromo-4-chloropyridine (36953-42-1) → 7-bromo-1H-pyrazolo[4,3-c]pyridine (1256821-58-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 2.5 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C

2.1: hydrazine hydrate / 1,2-dimethoxyethane / 120 °C / Sealed tube

With hydrazine hydrate; lithium diisopropyl amide; In tetrahydrofuran; 1,2-dimethoxyethane;

Reference yield:

pyridin-4-ol (626-64-2,157061-69-3) → 7-bromo-1H-pyrazolo[4,3-c]pyridine (1256821-58-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: N-Bromosuccinimide / tetrachloromethane / 30 h / 25 °C / Inert atmosphere

2.1: trichlorophosphate / 3 h / 70 °C / Inert atmosphere

3.1: tert-butylmagnesium chloride / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

3.2: 4 h / 20 °C / Inert atmosphere

4.1: hydrazine hydrate / dimethyl sulfoxide / 16 h / 130 - 140 °C

With N-Bromosuccinimide; tert-butylmagnesium chloride; hydrazine hydrate; trichlorophosphate; In tetrahydrofuran; tetrachloromethane; dimethyl sulfoxide;

upstream raw materials:

3-bromo-4-chloropyridine

5-bromo-4-chloro-pyridine-3-carbaldehyde

pyridin-4-ol

3,5-dibromo-4-hydroxypyridine

Downstream raw materials:

7-bromo-3-iodo-1H-pyrazolo[4,3-c]pyridine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1256821-58-5 7-BroMo-1H-pyrazolo[4,3-c...

Send

Send

Metric Ton KG G Pound L ML

Send

Send