1060802-24-5

Basic information

• Product Name: 5-broMo-4-chloronicotinaldehyde
• Synonyms: 5-broMo-4-chloronicotinaldehyde;5-Bromo-4-chloro-pyridine-3-carbaldehyde
• CAS NO: 1060802-24-5
• Molecular Formula: C₆H₃BrClNO
• Molecular Weight: 220.45112
• Mol File: 1060802-24-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-broMo-4-chloronicotinaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-broMo-4-chloronicotinaldehyde(1060802-24-5)
• EPA Substance Registry System: 5-broMo-4-chloronicotinaldehyde(1060802-24-5)

Safety Data

• Hazardous Substances Data: 1060802-24-5(Hazardous Substances Data)

Usage

General Description

5-bromo-4-chloronicotinaldehyde is a chemical compound with the molecular formula C6H3BrClNO. It is a versatile building block used in organic synthesis and medicinal chemistry. 5-broMo-4-chloronicotinaldehyde is a halogenated derivative of nicotinaldehyde, a heterocyclic aromatic aldehyde that is commonly used as a precursor in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. The bromine and chlorine substituents on the nicotinaldehyde ring impart unique physicochemical properties to 5-bromo-4-chloronicotinaldehyde, making it useful in various chemical and biological applications. 5-broMo-4-chloronicotinaldehyde has shown potential as a key intermediate in the development of novel pharmaceutical compounds and agrochemicals.

Upstream product

• 13626-17-0 3,5-dibromo-4-chloro-pyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 25813-25-6 3,5-dibromo-4-hydroxypyridine 
• 626-64-2 pyridin-4-ol 
• 36953-42-1 3-bromo-4-chloropyridine 

Downstream Products

• 1378039-92-9 4-azido-5-bromonicotinaldehyde 
• 1357946-27-0 7-bromo-3-iodo-1H-pyrazolo[4,3-c]pyridine 
• 1256821-58-5 7-bromo-1H-pyrazolo[4,3-c]pyridine 

Relevant articles and documents

TOLL-LIKE RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USE

The invention relates to compounds of formula (I): or a salt or solvate thereof, wherein the variables are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are antagonists of toll-like receptors such as TLR7, TLR8 and/or TLR9 that are useful for inhibiting immune response and treating diseases associated with undesirable immune response.

CONDENSED RING DERIVATIVE, AND PREPARATION METHOD, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE THEREOF

Disclosed are a condensed ring derivative, and a preparation method, an intermediate, a pharmaceutical composition and a use thereof. The condensed ring derivative of the present invention has a significant inhibitive effect on URAT1, which can effectively alleviate or treat hyperuricemia and other related diseases.

Derivatives of sulfur-containing heterocyclic carboxylic acids and preparation method and application thereof

The invention belongs to the field of medicines and particularly relates to derivatives of a series of sulfur-containing heterocyclic carboxylic acids, officinal salts thereof, a preparation method of pharmaceutically acceptable prodrugs, drug compositions including derivatives and application of the derivatives and the drug compositions in preparation of anti-gout drugs and treatment of related diseases.