CP 102

Base Information

• Chemical Name: CP 102
• CAS No.: 126055-13-8
• Molecular Formula: C₉H₁₃NO₃
• Molecular Weight: 183.207
• Mol file: 126055-13-8.mol

Synonyms:CP 102; CP102 (pharmaceutical)

Chemical Property of CP 102

Chemical Property:

• Vapor Pressure: 6.7E-06mmHg at 25°C
• Boiling Point: 338.3°Cat760mmHg
• Flash Point: 158.4°C
• PSA: 62.46000
• Density: 1.252g/cm³
• LogP: 0.10860

Purity/Quality:

98%min ^*data from raw suppliers

4(1H)-Pyridinone,2-ethyl-3-hydroxy-1-(2-hydroxyethyl)- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CP 102

There total 12 articles about CP 102 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[2'-(hydroxy)ethyl]-2-ethyl-3-benzyloxy-4(1H)-pyridinone (210244-51-2) → CP102 (126055-13-8)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol;

DOI:10.1021/acs.jmedchem.7b00346

Reference yield:

3-(benzyloxy)-2-ethyl-4H-pyran-4-one (111782-87-7) → CP102 (126055-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol; water / 18 h / Reflux

2: hydrogen; palladium on activated charcoal / methanol

With palladium on activated charcoal; hydrogen; sodium hydroxide; In methanol; ethanol; water;

DOI:10.1021/acs.jmedchem.7b00346

Reference yield:

2-ethyl-3-hydroxy-4-pyranone (4940-11-8) → CP102 (126055-13-8)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / methanol; water / 60 °C / Reflux

2: sodium hydroxide / ethanol; water / 18 h / Reflux

3: hydrogen; palladium on activated charcoal / methanol

With palladium on activated charcoal; hydrogen; sodium hydroxide; In methanol; ethanol; water;

DOI:10.1021/acs.jmedchem.7b00346

upstream raw materials:

1-[2'-(pivaloyloxy)ethyl]-2-ethyl-3-hydroxy-4(1H)-pyridinone

1-[2'-(hydroxy)ethyl]-2-ethyl-3-benzyloxy-4(1H)-pyridinone

3-(benzyloxy)-2-ethyl-4H-pyran-4-one

2-ethyl-3-hydroxy-4-pyranone

Refernces

• 1、 Battah, Sinan,Hider, Robert C.,MacRobert, Alexander J.,Dobbin, Paul S.,Zhou, Tao. "Hydroxypyridinone and 5-Aminolaevulinic Acid Conjugates for Photodynamic Therapy". . p. 3498 - 3510. Retrieved 2017/05/05.
• 2、 -. "Process for producing pyrid-4-ones". . . Retrieved 2008/06/13.