Succinylglutaminyl-valyl-valyl-alanyl-alanine-4-nitroanilide

Base Information

Chemical Name:Succinylglutaminyl-valyl-valyl-alanyl-alanine-4-nitroanilide
CAS No.:115700-57-7
Molecular Formula:C₃₁H₄₆N₈O₁₁
Molecular Weight:706.753
Hs Code.:
DSSTox Substance ID:DTXSID10151173
Wikidata:Q83017579
Mol file:115700-57-7.mol

Synonyms:SGVVAA-nitroanilide;succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide;succinylglutaminyl-valyl-valyl-alanyl-alanine-4-nitroanilide

Suppliers and Price of Succinylglutaminyl-valyl-valyl-alanyl-alanine-4-nitroanilide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Succinylglutaminyl-valyl-valyl-alanyl-alanine-4-nitroanilide

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1147.6°Cat760mmHg
Flash Point:647.8°C
PSA：319.25000
Density:1.304g/cm³
LogP:5.38680
XLogP3:0.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:19
Exact Mass:706.32860431
Heavy Atom Count:50
Complexity:1260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(=O)C(C)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)N)NC(=O)CCC(=O)O
Isomeric SMILES:C[C@@H](C(=O)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)CCC(=O)O)NC1=CC=C(C=C1)[N+](=O)[O-]

Technology Process of Succinylglutaminyl-valyl-valyl-alanyl-alanine-4-nitroanilide

There total 14 articles about Succinylglutaminyl-valyl-valyl-alanyl-alanine-4-nitroanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.5%

: 108-30-5
succinic acid anhydride

: 748095-60-5
H-Gln-Val-Val-Ala-Ala-pNA

: 115700-57-7
Suc-Gln-Val-Val-Ala-Ala-pNA

Guidance literature:: With pyridine; triethylamine; at 4 ℃;
DOI:10.1248/cpb.36.1982

Reference yield:

: {(S)-3-Carbamoyl-1-[(S)-2-methyl-1-((S)-2-methyl-1-{(S)-1-[(S)-1-(4-nitro-phenylcarbamoyl)-ethylcarbamoyl]-ethylcarbamoyl}-propylcarbamoyl)-propylcarbamoyl]-propyl}-carbamic acid tert-butyl ester

: 115700-57-7
Suc-Gln-Val-Val-Ala-Ala-pNA

Guidance literature:: Multi-step reaction with 2 steps

1: 1 h

2: 66.5 percent / pyridine, Et₃N / dimethylformamide / Ambient temperature

With pyridine; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1248/cpb.44.1599

Reference yield:

: 7763-16-8
N²-benzyloxycarbonyl-L-glutamine-(4-nitro-phenyl ester)

: 115700-57-7
Suc-Gln-Val-Val-Ala-Ala-pNA

Guidance literature:: Multi-step reaction with 3 steps

1: 78.9 percent / triethylamine / dimethylformamide / Ambient temperature

2: hydrogen bromide / acetic acid

3: 66.5 percent / pyridine, triethylamine / 4 °C

With pyridine; hydrogen bromide; triethylamine; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1248/cpb.36.1982