Ethyl dichlorothiophosphate

Base Information

• Chemical Name: Ethyl dichlorothiophosphate
• CAS No.: 1498-64-2
• Molecular Formula: C2H5 Cl2 O P S
• Molecular Weight: 179.007
• Hs Code.: 2931900090
• European Community (EC) Number: 216-100-4
• NSC Number: 91481
• DSSTox Substance ID: DTXSID6061733
• Nikkaji Number: J206.703J
• Wikidata: Q81989628
• Mol file: 1498-64-2.mol

Synonyms:Ethyl dichlorothiophosphate;1498-64-2;O-Ethyl dichlorothiophosphate;Ethyl phosphorodichloridothionate;ETHYLDICHLOROTHIOPHOSPHATE;O-Ethyl phosphorodichloridothioate;Ethyl thiophosphorodichloridate;Ethylphosphorothioic dichloride;O-Ethylthiophosphoryl dichloride;Ethyl phosphonodichloridothionate;O-Ethyl phosphorothiodichloridate;Phosphine sulfide, dichloroethoxy-;Monoethyldichlorothiophosphate;Phosphorodichloridothioic acid, O-ethyl ester;Ethyldichlorthiofosfat [Czech];Ethyldichlorthiofosfat;EINECS 216-100-4;NSC 91481;TL 429;14998-64-2;BRN 1702237;Phosphorodichloridothioicacid, O-ethyl ester;dichloro-ethoxy-sulfanylidene-lambda5-phosphane;O-Ethylester kyseliny dichlorthiofosforecne [Czech];O-Ethylester kyseliny dichlorthiofosforecne;4-01-00-01353 (Beilstein Handbook Reference);C2H5Cl2OPS;Ethoxythiophosphoryl chloride;Ethoxydichlorophosphine sulfide;C2-H5-Cl2-O-P-S;SCHEMBL1203334;DTXSID6061733;Ethyl dichlorothiophosphate, 95%;NSC91481;NSC-91481;LS-108023;FT-0737398;3-(2,4-DIMETHYL-5-CARBOXY-1H-PYRROLE-3-YL)PROPANOICACID

Chemical Property of Ethyl dichlorothiophosphate

Chemical Property:

• Vapor Pressure: 10 mm Hg ( 55 °C)
• Refractive Index: n20/D 1.504(lit.)
• Boiling Point: 180.5°Cat760mmHg
• Flash Point: 63°C
• PSA: 51.13000
• Density: 1.458g/cm³
• LogP: 3.37560
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 177.9175783
• Heavy Atom Count: 7
• Complexity: 89.7

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl dichlorothiophosphate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 23/24/25-34-23/24-22
• Safety Statements: 22-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOP(=S)(Cl)Cl
• Uses: Ethyl Dichlorothiophosphate is used in the preparation of polyclonal antibody for insecticide chlorpyrifos. It is also used in the mutagenicity study of new organophosphorus pesticides.

Technology Process of Ethyl dichlorothiophosphate

There total 5 articles about Ethyl dichlorothiophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

ethanol (64-17-5) → O-ethyl dichlorothiophosphate (1498-64-2)

Guidance literature:

With trichlorophosphate;

DOI:10.1080/10426509708040496

Reference yield:

ethanol (64-17-5) → O-ethyl dichlorothiophosphate (1498-64-2) + O,O,O-triethyl phosphorothioate (126-68-1) + diethyl phosphorochloridothioate (2524-04-1)

Guidance literature:

With trichlorophosphate; at 20 ℃; Product distribution; multistep reaction; varying of molar ratio of components; time taken in the addition of alcohol; consumption time of reactants; alcoholysis of PSCl₃ (estimation of rel. rates);

Reference yield:

aluminum ethoxide (555-75-9) → O-ethyl dichlorothiophosphate (1498-64-2)

Guidance literature:

With trichlorothiophosphine; benzene;

upstream raw materials:

ethanol

aluminum ethoxide

trichlorothiophosphine

Downstream raw materials:

O-Aethyl-N.N'-diaethylen-phosphordiamidothionat

O-ethyl-O-(4-nitrophenyl)thiophosphorochloride

diethyl phosphorochloridothioate

O-ethyl O-methyl O-p-nitrophenylthiophosphate

Refernces

• 1、 Quin, Louis D.,Hermann, Petr,Jankowski, Stefan. "Generation of ethyl metathiophosphate by thermal fragmentation of O-ethyl N-substituted phosphoramidothioates". . p. 3944 - 3950. Retrieved 1996.
• 2、 -. "Organophosphorus hapten, wide-spectrum polyspecific antigen, antibody and preparation method and application of hapten, antigen and antibody". Paragraph 0058. . Retrieved 2017/12/06.
• 3、 Abdel-Gawad,Afifi,Abdel-Hameed,Hegazi. "Distribution and degradation of 14C-ethyl prothiofos in a potato plant and the effect of processing". experimental part. p. 2734 - 2751. Retrieved 2009/09/06.