4-Iodo-2-(trifluoromethyl)benzoic acid

Base Information

Chemical Name:4-Iodo-2-(trifluoromethyl)benzoic acid
CAS No.:954815-11-3
Molecular Formula:C8H4F3IO2
Molecular Weight:316.018
Hs Code.:2916310090
DSSTox Substance ID:DTXSID50589916
Wikidata:Q82483556
Mol file:954815-11-3.mol

Synonyms:4-Iodo-2-(trifluoromethyl)benzoic acid;954815-11-3;MFCD09881756;2-(trifluoroMethyl)-4-iodobenzoic acid;4-Iodo-2-(trifluoromethyl)benzoicacid;SCHEMBL695647;DTXSID50589916;4-Iodo-2-trifluoromethylbenzoic acid;AKOS000109366;DS-17858;SY113227;DB-292037;CS-0041031

Suppliers and Price of 4-Iodo-2-(trifluoromethyl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Iodo-2-(trifluoromethyl)benzoicAcid
25mg
$ 45.00

SynQuest Laboratories
4-Iodo-2-(trifluoromethyl)benzoic acid
1 g
$ 136.00

SynQuest Laboratories
4-Iodo-2-(trifluoromethyl)benzoic acid
5 g
$ 264.00

Matrix Scientific
4-Iodo-2-(trifluoromethyl)benzoic acid
1g
$ 405.00

Crysdot
4-Iodo-2-(trifluoromethyl)benzoicacid 95+%
25g
$ 408.00

Chemenu
4-Iodo-2-(trifluoromethyl)benzoicacid 95%
100g
$ 1075.00

Chemenu
4-Iodo-2-(trifluoromethyl)benzoicacid 95%
25g
$ 411.00

Chemenu
4-Iodo-2-(trifluoromethyl)benzoicacid 95%
10g
$ 206.00

Chemenu
4-Iodo-2-(trifluoromethyl)benzoicacid 95%
5g
$ 122.00

Chemcia Scientific
4-Iodo-2-trifluoromethyl-benzoicacid ＞97%
5 G
$ 95.00

Total 15 raw suppliers

Chemical Property of 4-Iodo-2-(trifluoromethyl)benzoic acid

Chemical Property:

PSA：37.30000
LogP:3.00820
Storage Temp.:2-8°C(protect from light)
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:315.92081
Heavy Atom Count:14
Complexity:229

Purity/Quality:

97% ^*data from raw suppliers

4-Iodo-2-(trifluoromethyl)benzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1I)C(F)(F)F)C(=O)O

Technology Process of 4-Iodo-2-(trifluoromethyl)benzoic acid

There total 2 articles about 4-Iodo-2-(trifluoromethyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 101066-87-9
4-iodo-2-(trifluoromethyl)benzonitrile

: 954815-11-3
4-iodo-2-(trifluoromethyl)benzoic acid

Guidance literature:: 4-iodo-2-(trifluoromethyl)benzonitrile; With water; sodium hydroxide; In ethanol; for 6h; Reflux;

With hydrogenchloride; In ethanol; water;
DOI:10.1021/ol503189j

Reference yield:

: 3058-39-7
4-iodobenzonitrile

: 954815-11-3
4-iodo-2-(trifluoromethyl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: silver carbonate; sodium carbonate; dipotassium peroxodisulfate / dichloromethane / 10 h / 120 °C / Schlenk technique; Sealed tube

2: sodium hydroxide; water / ethanol / 6 h / Reflux

With dipotassium peroxodisulfate; water; sodium carbonate; silver carbonate; sodium hydroxide; In ethanol; dichloromethane;
DOI:10.1021/ol503189j

Reference yield: 60.0%

: 954815-11-3
4-iodo-2-(trifluoromethyl)benzoic acid

: 1299482-96-4
N-{2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]ethyl}-acrylamide

: 1299482-97-5
4-[(E)-3-oxo-3-[[2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]ethyl]amino]prop-1-enyl]-2-(trifluoromethyl)benzoic acid

Guidance literature:: With triethylamine; triphenylphosphine; palladium diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 5h; Inert atmosphere;