(3-fluorooxetan-3-yl)methanol

Base Information

• Chemical Name: (3-fluorooxetan-3-yl)methanol
• CAS No.: 865451-85-0
• Molecular Formula: C4H7FO2
• Molecular Weight: 106.097
• Hs Code.: 2932999099
• Mol file: 865451-85-0.mol

Synonyms:(3-fluorooxetan-3-yl)methanol;

Chemical Property of (3-fluorooxetan-3-yl)methanol

Chemical Property:

• Boiling Point: 137.5±15.0 °C(Predicted)
• PKA: 14.58±0.10(Predicted)
• PSA: 29.46000
• Density: 1.24±0.1 g/cm3(Predicted)
• LogP: -0.28280
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C

Purity/Quality:

97% ^*data from raw suppliers

(3-fluorooxetan-3-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,N
• Hazard Codes: T,N
• Statements: 22-36/37/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-fluorooxetan-3-yl)methanol

There total 3 articles about (3-fluorooxetan-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(3-fluorooxetan-3-yl)methyl 4-methylbenzenesulfonate → (3-fluorooxetan- 3-yl) methanol (865451-85-0)

Guidance literature:

With methanol; magnesium; at 20 ℃; for 10h;

Reference yield: 83.0%

tert-butyl[(3-fluorooxetan-3-yl)methoxy]diphenylsilane (1620017-27-7) → (3-fluorooxetan- 3-yl) methanol (865451-85-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2014.06.024

Reference yield: 70.0%

3-benzyloxymethyl-3-fluorooxetane (865451-84-9) → (3-fluorooxetan- 3-yl) methanol (865451-85-0)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; acetic acid; for 24h; under 2068.65 Torr;

upstream raw materials:

3-benzyloxymethyl-3-fluorooxetane

tert-butyl[(3-fluorooxetan-3-yl)methoxy]diphenylsilane

Downstream raw materials:

3-(bromomethyl)-3-fluorooxetane