(S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide

Base Information

Chemical Name:(S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide
CAS No.:1208552-99-1
Molecular Formula:C₂₁H₂₁ClN₂OS
Molecular Weight:384.93
Hs Code.:2934100090
Mol file:1208552-99-1.mol

Synonyms:CFMB;(S)-2-(4-chlorophenyl)-3,3-diMethyl-N-(5-phenylthiazol-2-yl)butanaMide;(2S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenyl-1,3-thiazol-2-yl)butanamide;Benzeneacetamide, 4-chloro-α-(1,1-dimethylethyl)-N-(5-phenyl-2-thiazolyl)-, (αS)-

Suppliers and Price of (S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S)-2-(4-CHLOROPHENYL)-3,3-DIMETHYL-N-(5-PHENYLTHIAZOL-2-YL)BUTANAMIDE 95.00%
1G
$ 1872.15

American Custom Chemicals Corporation
(S)-2-(4-CHLOROPHENYL)-3,3-DIMETHYL-N-(5-PHENYLTHIAZOL-2-YL)BUTANAMIDE 95.00%
5MG
$ 505.22

Total 4 raw suppliers

Chemical Property of (S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide

Chemical Property:

PKA:8.81±0.50(Predicted)
PSA：70.23000
Density:1.241±0.06 g/cm3(Predicted)
LogP:6.30490

Purity/Quality:

≥99% ^*data from raw suppliers

(S)-2-(4-CHLOROPHENYL)-3,3-DIMETHYL-N-(5-PHENYLTHIAZOL-2-YL)BUTANAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide

There total 2 articles about (S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 39136-63-5
5-phenyl-1,3-thiazol-2-amine

: 1208553-23-4
(S)-2-(4-chlorophenyl)-3,3-dimethylbutanoic acid

: 1208552-99-1
(S)-2-(4-chlorophenyl)-3, 3-dimethyl–N- (5-phenylthiazol-2-yl) butanamide

Guidance literature:: With 2,4,6-trimethyl-pyridine; oxalyl dichloride; In N,N-dimethyl-formamide; at -15 ℃; for 2h;
DOI:10.1016/j.bmcl.2009.11.112

Reference yield:

: 96-50-4
2-thiazolylamine

: 1208553-23-4
(S)-2-(4-chlorophenyl)-3,3-dimethylbutanoic acid

: 1208552-99-1
(S)-2-(4-chlorophenyl)-3, 3-dimethyl–N- (5-phenylthiazol-2-yl) butanamide

: C₂₁H₂₁ClN₂OS

Guidance literature:: With oxalyl dichloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 20 ℃; optical yield given as %ee;
DOI:10.1016/j.bmcl.2009.11.112