benzyl (3S,4S)-4-aMino-3-hydroxypiperidine-1-carboxylate

Base Information

Chemical Name:benzyl (3S,4S)-4-aMino-3-hydroxypiperidine-1-carboxylate
CAS No.:1007596-63-5
Molecular Formula:C13H18N2O3
Molecular Weight:250.298
Hs Code.:
Mol file:1007596-63-5.mol

Synonyms:Benzyl (3S,4S)-4-amino-3-hydroxypiperidine-1-carboxylate;

Suppliers and Price of benzyl (3S,4S)-4-aMino-3-hydroxypiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
benzyl(3S,4S)-4-amino-3-hydroxypiperidine-1-carboxylate 97%
1 g
$ 880.00

Chemenu
(3S,4S)-Benzyl4-amino-3-hydroxypiperidine-1-carboxylate 95%
1g
$ 583.00

Alichem
(3S,4S)-Benzyl4-amino-3-hydroxypiperidine-1-carboxylate
1g
$ 547.18

Total 10 raw suppliers

Chemical Property of benzyl (3S,4S)-4-aMino-3-hydroxypiperidine-1-carboxylate

Chemical Property:

PSA：75.79000
LogP:1.35530

Purity/Quality:

99%, ^*data from raw suppliers

benzyl(3S,4S)-4-amino-3-hydroxypiperidine-1-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of benzyl (3S,4S)-4-aMino-3-hydroxypiperidine-1-carboxylate

There total 2 articles about benzyl (3S,4S)-4-aMino-3-hydroxypiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 167832-25-9
trans(±)benzyl-4-azido-3-hydroxypiperidine-1-carboxylate

: 1007596-63-5
benzyl (3S,4S)-4-amino-3-hydroxy-piperidine-1-carboxylate

: 959617-87-9
benzyl (3R,4R)-4-amino-3-hydroxy-piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C

1.2: 20 °C

2.1: chiral column Column: AD 250 / Resolution of racemate

With triphenylphosphine; In tetrahydrofuran;
DOI:10.1021/jm500462x

Reference yield:

: (+/-)-trans-benzyl 4-amino-3-hydroxypiperdine-1-carboxylate

: 1007596-63-5
benzyl (3S,4S)-4-amino-3-hydroxy-piperidine-1-carboxylate

: 959617-87-9
benzyl (3R,4R)-4-amino-3-hydroxy-piperidine-1-carboxylate

Guidance literature:: With chiral column Column: AD 250; Resolution of racemate;
DOI:10.1021/jm500462x

Reference yield: 76.0%

: 1007596-63-5
benzyl (3S,4S)-4-amino-3-hydroxy-piperidine-1-carboxylate

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: benzyl (3S,4S)-4-(cyclohexylamino)-3-hydroxypiperidine-1-carboxylate

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 24h;
DOI:10.1021/acs.jmedchem.8b01679