Ethyl 4,6-dichloro-2-methylnicotinate

Base Information

Chemical Name:Ethyl 4,6-dichloro-2-methylnicotinate
CAS No.:686279-09-4
Molecular Formula:C9H9Cl2NO2
Molecular Weight:234.082
Hs Code.:2933399090
European Community (EC) Number:854-156-7
DSSTox Substance ID:DTXSID70383039
Wikidata:Q72466924
Mol file:686279-09-4.mol

Synonyms:ETHYL 4,6-DICHLORO-2-METHYLNICOTINATE;686279-09-4;4,6-DICHLORO-2-METHYL-NICOTINIC ACID ETHYL ESTER;ethyl 4,6-dichloro-2-methylpyridine-3-carboxylate;MFCD05666193;4,6-dichloro-2-methyl-3-carbethoxypyridine;Ethyl 4,6-dichloro-2-methyl-pyridine-3-carboxylate;SCHEMBL612669;DTXSID70383039;LNIMLSAAPISOEC-UHFFFAOYSA-N;AMY20490;BCP21387;AKOS015950566;CS-W003247;AC-27883;DS-16897;SY006217;ETHYL4,6-DICHLORO-2-METHYLNICOTINATE;FT-0698833;4,6-dichloro-2-methyl nicotinic acid ethyl ester;A849274;4,6-DICHLORO-2-METHYLNICOTINIC ACID ETHYL ESTER

Suppliers and Price of Ethyl 4,6-dichloro-2-methylnicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl4,6-dichloro-2-methylnicotinate
250mg
$ 50.00

SynQuest Laboratories
Ethyl 4,6-dichloro-2-methylnicotinate 97%
25 g
$ 596.00

SynQuest Laboratories
Ethyl 4,6-dichloro-2-methylnicotinate 97%
5 g
$ 154.00

SynQuest Laboratories
Ethyl 4,6-dichloro-2-methylnicotinate 97%
1 g
$ 100.00

Matrix Scientific
Ethyl 4,6-dichloro-2-methylnicotinate
5g
$ 285.00

Matrix Scientific
Ethyl 4,6-dichloro-2-methylnicotinate
1g
$ 90.00

Crysdot
Ethyl4,6-dichloro-2-methylnicotinate 97%
10g
$ 134.00

Crysdot
Ethyl4,6-dichloro-2-methylnicotinate 97%
25g
$ 320.00

Chemenu
Ethyl4,6-dichloro-2-methylnicotinate 97%
10g
$ 262.00

Chemenu
Ethyl4,6-dichloro-2-methylnicotinate 97%
5g
$ 173.00

Total 39 raw suppliers

Chemical Property of Ethyl 4,6-dichloro-2-methylnicotinate

Chemical Property:

Boiling Point:283℃
PKA:-0.22±0.10(Predicted)
Flash Point:125℃
PSA：39.19000
Density:1.320
LogP:2.87350
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:233.0010339
Heavy Atom Count:14
Complexity:213

Purity/Quality:

97% ^*data from raw suppliers

Ethyl4,6-dichloro-2-methylnicotinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(N=C(C=C1Cl)Cl)C

Technology Process of Ethyl 4,6-dichloro-2-methylnicotinate

There total 4 articles about Ethyl 4,6-dichloro-2-methylnicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 3950-10-5
5-Ethoxycarbonyl-4-hydroxy-6-methyl-pyridin-2(1H)-on

: 686279-09-4
ethyl 4,6-dichloro-2-methylpyridine-3-carboxylate

Guidance literature:: With N-benzyl-N,N,N-triethylammonium chloride; trichlorophosphate; In acetonitrile; at 20 ℃; Inert atmosphere; Reflux;
DOI:10.1021/jm900802y

Reference yield: 62.0%

: 3950-10-5,70254-48-7,70254-49-8
4,6-dihydroxy-2-methyl nicotinic acid ethyl ester

: 686279-09-4
ethyl 4,6-dichloro-2-methylpyridine-3-carboxylate

Guidance literature:: With trichlorophosphate; at 90 ℃; for 5h; Inert atmosphere;

Reference yield:

: 626-34-6,7318-00-5,41867-20-3
ethyl aminocrotonate

: 686279-09-4
ethyl 4,6-dichloro-2-methylpyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 2,4,6-Trichlorophenol; trichlorophosphate / 3 h / 100 °C

1.2: 1.5 h / 155 °C

2.1: trichlorophosphate / 2.5 h / 140 °C

With 2,4,6-Trichlorophenol; trichlorophosphate;