Benzotriazole1.0

Base Information

• Chemical Name: Benzotriazole1.0
• CAS No.: 92283-88-0
• Molecular Formula: C13H14O4
• Molecular Weight: 234.252
• Mol file: 92283-88-0.mol

Synonyms:1.5;Benzotriazole1.0;2,3-Dianhydro-4,6-O-benzylidene-D-allitol;1,5:2,3-dianhydro-4,6-O-[(R)-phenylMethylene]-D-Allitol

Chemical Property of Benzotriazole1.0

Chemical Property:

• Boiling Point: 369.1±37.0 °C (760 mmHg)
• PSA: 40.22000
• Density: 1.262±0.06 g/cm3 (20 °C, 760 mmHg)
• LogP: 1.26680

Purity/Quality:

98%Min ^*data from raw suppliers

1-[5- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzotriazole1.0

There total 2 articles about Benzotriazole1.0 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,3-di-O-p-tolylsulphonyl-4,6-O-benzylidene-1,5-anhydro-D-glucitol (65371-07-5) → 1,5:2,3-dianhydro-4,6-O-benzylidene-D-allitol (92283-88-0)

Guidance literature:

With sodium methylate; In dichloromethane; at 20 ℃; for 17h;

Reference yield:

1,5-anhydro-4,6-O-(R)-benzylidene-D-glucitol (65391-44-8) → 1,5:2,3-dianhydro-4,6-O-benzylidene-D-allitol (92283-88-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / pyridine / 96 h

2: 97 percent / 2.33M methanolic NaOMe / CH₂Cl₂ / 17 h / 20 °C

With sodium methylate; In pyridine; dichloromethane;

Reference yield: 99.0%

thymin (65-71-4,28806-14-6,691841-57-3) + 1,5:2,3-dianhydro-4,6-O-benzylidene-D-allitol (92283-88-0) → 1,5-anhydro-4,6-O-benzylidene-2-deoxy-2-(thymin-1-yl)-D-altro-hexitol (401906-49-8)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 85 ℃; for 36h;

DOI:10.1021/ja207086x

upstream raw materials:

2,3-di-O-p-tolylsulphonyl-4,6-O-benzylidene-1,5-anhydro-D-glucitol

1,5-anhydro-4,6-O-(R)-benzylidene-D-glucitol

Downstream raw materials:

O⁴,O⁶-((R)-benzyliden)-1,5-anhydro-D-altritol

2-deoxy-2-C-methyl-4,6-O-benzylidene-1,5-anhydro-D-altritol

2-deoxy-2-C-vinyl-4,6-O-benzylidene-1,5-anhydro-D-altritol

2-deoxy-2-C-vinyl-4,6-O-benzylidene-1,5-anhydro-D-allitol

Refernces