6-(Pyridin-3-yloxy)pyridin-3-amine

Base Information

Chemical Name:6-(Pyridin-3-yloxy)pyridin-3-amine
CAS No.:99185-50-9
Molecular Formula:C10H9 N3 O
Molecular Weight:187.19796
Hs Code.:2933399090
European Community (EC) Number:853-088-5
DSSTox Substance ID:DTXSID40243979
Wikidata:Q83128207
Mol file:99185-50-9.mol

Synonyms:6-(Pyridin-3-yloxy)pyridin-3-amine;99185-50-9;6-pyridin-3-yloxypyridin-3-amine;Pyridine, 5-amino-2,3'-oxydi-;5-Amino-2,3'-oxydipyridine;BRN 0153005;4-22-00-05578 (Beilstein Handbook Reference);Maybridge1_001863;SCHEMBL3092042;HMS546M15;DTXSID40243979;YGWSGSCQMYIFRQ-UHFFFAOYSA-N;6-(3-Pyridyloxy)pyridine-3-amine;5-amino-2-(pyrid-3-yloxy)pyridine;AKOS005207971;6-(pyridine-3-yloxy)pyridine-3-amine;SB53996;TS-02633;LS-130252;CS-0234904;EN300-149601;F2108-0164;Z381429142

Suppliers and Price of 6-(Pyridin-3-yloxy)pyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(pyridin-3-yloxy)pyridin-3-amine
50mg
$ 90.00

TRC
6-(pyridin-3-yloxy)pyridin-3-amine
5mg
$ 45.00

Matrix Scientific
6-(Pyridin-3-yloxy)pyridin-3-amine 97%
1g
$ 360.00

Crysdot
6-(Pyridin-3-yloxy)pyridin-3-amine 97%
5g
$ 749.00

Atlantic Research Chemicals
6-(Pyridin-3-yloxy)pyridin-3-amine 95%
1gm:
$ 137.85

AK Scientific
6-(Pyridin-3-yloxy)pyridin-3-amine
250mg
$ 273.00

Total 4 raw suppliers

Chemical Property of 6-(Pyridin-3-yloxy)pyridin-3-amine

Chemical Property:

Vapor Pressure:1.64E-06mmHg at 25°C
Boiling Point:397°Cat760mmHg
Flash Point:193.9°C
PSA：61.03000
Density:1.258g/cm³
LogP:2.43230
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:187.074561919
Heavy Atom Count:14
Complexity:177

Purity/Quality:

97% ^*data from raw suppliers

6-(pyridin-3-yloxy)pyridin-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CN=C1)OC2=NC=C(C=C2)N

Technology Process of 6-(Pyridin-3-yloxy)pyridin-3-amine

There total 5 articles about 6-(Pyridin-3-yloxy)pyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 99073-54-8
(5-nitro-[2]pyridyl)-[3]pyridyl ether

: 99185-50-9
5-amino-2-(pyridin-3-yloxy)pyridine

Guidance literature:: With hydrogenchloride; tin(ll) chloride; In ethanol; water; at 50 ℃; for 3h;

Reference yield:

: 99185-50-9
5-amino-2-(pyridin-3-yloxy)pyridine

Guidance literature:: With methanol; iron; acetic acid;
DOI:10.1021/ja01197a063

Reference yield:

: 109-00-2
3-HYDROXYPYRIDINE

: 99185-50-9
5-amino-2-(pyridin-3-yloxy)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 4 h / 0 - 20 °C / Inert atmosphere

2: hydrogenchloride; tin(II) chloride dihdyrate / ethanol; water / 2 h / 70 °C / Inert atmosphere

With hydrogenchloride; tin(II) chloride dihdyrate; sodium hydride; In ethanol; water; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/acsmedchemlett.7b00443