N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide

Base Information

Chemical Name:N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide
CAS No.:849513-58-2
Molecular Formula:C18H17N3OS
Molecular Weight:323.418
Hs Code.:2934100090
Mol file:849513-58-2.mol

Synonyms:N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide

Suppliers and Price of N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-[4-(2,4,6-TRIMETHYLPHENYL)-2-THIAZOLYL]-4-PYRIDINECARBOXAMIDE 95+%
1g
$ 665.00

Chemenu
N-(4-mesitylthiazol-2-yl)isonicotinamide 95%
1g
$ 622.00

American Custom Chemicals Corporation
N-[4-(2,4,6-TRIMETHYLPHENYL)-2-THIAZOLYL]-4-PYRIDINECARBOXAMIDE 95.00%
5MG
$ 502.79

Alichem
N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide
1g
$ 665.00

Alichem
N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide
50mg
$ 172.48

Alichem
N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide
250mg
$ 513.13

AK Scientific
N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide
250mg
$ 262.00

Total 7 raw suppliers

Chemical Property of N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide

Chemical Property:

PKA:5.41±0.70(Predicted)
PSA：83.12000
Density:1.251±0.06 g/cm3(Predicted)
LogP:4.45560

Purity/Quality:

97% ^*data from raw suppliers

N-[4-(2,4,6-TRIMETHYLPHENYL)-2-THIAZOLYL]-4-PYRIDINECARBOXAMIDE 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide

There total 5 articles about N-[4-(2,4,6-Trimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 55-22-1
pyridine-4-carboxylic acid

: 81529-60-4
4-(2,4,6-trimethylphenyl)thiazol-2-ylamine

: 849513-58-2
N-(4-mesitylthiazol-2-yl)isonicotinamide

Guidance literature:: pyridine-4-carboxylic acid; With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; for 2h;

4-(2,4,6-trimethylphenyl)thiazol-2-ylamine; In dichloromethane; at 20 ℃;

Reference yield: 77.0%

: 14254-57-0
4-(chlorocarbonyl)pyridine

: 81529-60-4
4-(2,4,6-trimethylphenyl)thiazol-2-ylamine

: 849513-58-2
N-(4-mesitylthiazol-2-yl)isonicotinamide

Guidance literature:: With dmap; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/jm401990s

Reference yield:

: 4225-92-7
2-bromo-1-(2,4,6-trimethylphenyl)ethanone

: 849513-58-2
N-(4-mesitylthiazol-2-yl)isonicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol / 2 h / Reflux

2.1: 1,1'-carbonyldiimidazole / dichloromethane / 2 h / 20 °C

2.2: 20 °C

With 1,1'-carbonyldiimidazole; In ethanol; dichloromethane;