2-Chloro-1-ethynyl-4-fluorobenzene

Base Information

Chemical Name:2-Chloro-1-ethynyl-4-fluorobenzene
CAS No.:1057670-02-6
Molecular Formula:C8H4ClF
Molecular Weight:154.571
Hs Code.:
DSSTox Substance ID:DTXSID201296872
Mol file:1057670-02-6.mol

Synonyms:2-CHLORO-1-ETHYNYL-4-FLUOROBENZENE;1057670-02-6;2-chloro-1-ethynyl-4-fluoro-benzene;Benzene, 2-chloro-1-ethynyl-4-fluoro-;starbld0045564;SCHEMBL2784467;DTXSID201296872;AKOS010651528;AT36286;A18058;EN300-1983208;A1-58712

Suppliers and Price of 2-Chloro-1-ethynyl-4-fluorobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-1-ETHYNYL-4-FLUOROBENZENE 95.00%
5MG
$ 495.33

Total 6 raw suppliers

Chemical Property of 2-Chloro-1-ethynyl-4-fluorobenzene

Chemical Property:

PSA：0.00000
LogP:2.46040
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:153.9985560
Heavy Atom Count:10
Complexity:158

Purity/Quality:

97% ^*data from raw suppliers

2-CHLORO-1-ETHYNYL-4-FLUOROBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1=C(C=C(C=C1)F)Cl

Technology Process of 2-Chloro-1-ethynyl-4-fluorobenzene

There total 1 articles about 2-Chloro-1-ethynyl-4-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.1%

: 84194-36-5
2-chloro-4-fluorobenzaldehyde

: 90965-06-3
dimethyl 1-(1-diazo-2-oxopropyl)phosphonate

: 1057670-02-6
2-chloro-1-ethynyl-4-fluorobenzene

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 16h;

Reference yield: 88.0%

: 1057670-02-6
2-chloro-1-ethynyl-4-fluorobenzene

: 4-(2-azido-2-(dibenzo[b,d]thiophen-2-yl)ethyl)piperidine

: 1-(2-(4-(2-chloro-4-fluorophenyl)-1H-1,2,3-triazol-1-yl)-2-(dibenzo[b,d]thiophen-2-yl)ethyl)piperidine

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃; regioselective reaction;
DOI:10.1016/j.bmcl.2016.04.015

Reference yield: 85.0%

: 1057670-02-6
2-chloro-1-ethynyl-4-fluorobenzene

: 4-(2-azido-2-(dibenzo[b,d]thiophen-2-yl)ethyl)thiomorpholine

: 4-(2-(4-(2-chloro-4-fluorophenyl)-1H-1,2,3-triazol-1-yl)-2-(dibenzo[b,d]thiophen-2-yl)ethyl)thiomorpholine

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃; regioselective reaction;
DOI:10.1016/j.bmcl.2016.04.015