2-(2-Aminoethyl) Rhodamine B amide

Base Information

• Chemical Name: 2-(2-Aminoethyl) Rhodamine B amide
• CAS No.: 950846-89-6
• Molecular Formula: C30H36N4O2
• Molecular Weight: 484.641
• Hs Code.: 32049010
• Mol file: 950846-89-6.mol

Synonyms:2-(2-AMINOETHYL)-3',6'-BIS(DIETHYLAMINO)SPIRO[ISOINDOLINE-1,9'-XANTHEN]-3-ONE;

Chemical Property of 2-(2-Aminoethyl) Rhodamine B amide

Chemical Property:

• Melting Point: 217-219 °C
• Boiling Point: 676.5±55.0 °C(Predicted)
• PKA: 8.82±0.10(Predicted)
• PSA: 62.04000
• Density: 1.24±0.1 g/cm3(Predicted)
• LogP: 5.82930
• Storage Temp.: Room Temperature, under inert atmosphere
• Solubility.: Chloroform (Slightly)

Purity/Quality:

99.0% ^*data from raw suppliers

2-(2-Aminoethyl)-3'',6''-bis(diethylamino)spiro[isoindoline-1,9''-xanthen]-3-one(>80%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• General Description: 2-(2-Aminoethyl) Rhodamine B amide is a rhodamine-based derivative that functions as a highly sensitive and selective fluorescent chemosensor for metal ions, particularly Hg2?. It operates through a spirolactam ring-opening mechanism upon binding to Hg2?, resulting in a visible color change and strong fluorescence emission. This probe enables rapid detection (within seconds) with a low detection limit (nanomolar range) and has been successfully applied in cellular imaging, demonstrating its utility for monitoring Hg2? in biological systems. Additionally, its reversible binding allows for potential applications in environmental and analytical chemistry.

Technology Process of 2-(2-Aminoethyl) Rhodamine B amide

There total 10 articles about 2-(2-Aminoethyl) Rhodamine B amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

rhodamine B (81-88-9) + ethylenediamine (107-15-3,85404-18-8) → rhodamine B ethylenediamine (950846-89-6)

Guidance literature:

In ethanol; for 16h; Reflux;

DOI:10.1039/c5cc04508h

Reference yield: 95.0%

rhodamine B (509-34-2) + ethylenediamine (107-15-3,85404-18-8) → rhodamine B ethylenediamine (950846-89-6)

Guidance literature:

for 24h; Reflux;

DOI:10.1021/acs.biomac.0c00126

Reference yield: 92.0%

rhodamine B (4344-42-7) + ethylenediamine (107-15-3,85404-18-8) → rhodamine B ethylenediamine (950846-89-6)

Guidance literature:

In ethanol; for 12h; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.bmc.2014.12.070

upstream raw materials:

rhodamine B

ethylenediamine

rhodamine B

rhodamine B

Downstream raw materials:

{9-[2-(2-amino-ethylcarbamoyl)-phenyl]-6-diethylamino-xanthen-3-ylidene}-diethyl-ammonium

C₃₇H₄₁BrN₄O₂