1-(Dimethoxymethyl)-2-iodobenzene

Base Information

Chemical Name:1-(Dimethoxymethyl)-2-iodobenzene
CAS No.:933672-30-1
Molecular Formula:C9H11IO2
Molecular Weight:278.09
Hs Code.:2909309090
DSSTox Substance ID:DTXSID90573152
Nikkaji Number:J3.229.218F
Wikidata:Q82461747
Mol file:933672-30-1.mol

Synonyms:1-(dimethoxymethyl)-2-iodobenzene;933672-30-1;2-Iodobenzaldehyde dimethyl acetal;SCHEMBL3213376;DTXSID90573152;1-(dimethoxymethyl)-2-iodo- Benzene;A854389

Suppliers and Price of 1-(Dimethoxymethyl)-2-iodobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(Dimethoxymethyl)-2-iodobenzene 95+%
5g
$ 706.00

American Custom Chemicals Corporation
1-(DIMETHOXYMETHYL)-2-IODOBENZENE 95.00%
5MG
$ 501.68

Alichem
1-(Dimethoxymethyl)-2-iodobenzene
5g
$ 780.15

Total 7 raw suppliers

Chemical Property of 1-(Dimethoxymethyl)-2-iodobenzene

Chemical Property:

Vapor Pressure:0.0339mmHg at 25°C
Boiling Point:250.6°C at 760 mmHg
Flash Point:105.4°C
PSA：18.46000
Density:1.595g/cm³
LogP:2.58260
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:277.98038
Heavy Atom Count:12
Complexity:126

Purity/Quality:

97% ^*data from raw suppliers

1-(Dimethoxymethyl)-2-iodobenzene 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(C1=CC=CC=C1I)OC

Technology Process of 1-(Dimethoxymethyl)-2-iodobenzene

There total 3 articles about 1-(Dimethoxymethyl)-2-iodobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 35849-09-3
o-bromobenzaldehyde dimethyl acetal

: 933672-30-1
1-iodo-2-(dimethoxymethyl)benzene

Guidance literature:: o-bromobenzaldehyde dimethyl acetal; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

With iodine; In tetrahydrofuran; hexane; at -78 - 25 ℃; Inert atmosphere;
DOI:10.1021/ol1029047

Reference yield:

: 6630-33-7
ortho-bromobenzaldehyde

: 933672-30-1
1-iodo-2-(dimethoxymethyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: silica supported perchloric acid / 5 h / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

2.2: -78 - 25 °C / Inert atmosphere

With n-butyllithium; silica supported perchloric acid; In tetrahydrofuran; hexane;
DOI:10.1021/ol1029047

Reference yield:

: 26260-02-6
2-iodobenzaldehyde

: 149-73-5
trimethyl orthoformate

: 933672-30-1
1-iodo-2-(dimethoxymethyl)benzene

Guidance literature:: With zinc(II) chloride; In tert-butyl methyl ether; cyclohexane; for 16h; Sealed tube; Reflux;
DOI:10.1021/acs.joc.7b02862