2,3,5,6-TetraMethylfluorobenzene

Base Information

• Chemical Name: 2,3,5,6-TetraMethylfluorobenzene
• CAS No.: 319-92-6
• Molecular Formula: C₁₀H₁₃F
• Molecular Weight: 152.212
• Mol file: 319-92-6.mol

Synonyms:3-fluoro-1,2,4,5-tetramethyl-benzene;3-fluoro-1,1,3,5,5-pentanitropentane;3-Fluor-1,2,4,5-tetramethyl-benzol;1-fluoro-2,3,5,6-tetramethylbenzene;Pentane,3-fluoro-1,1,1,3,5,5,5-heptanitro;3-Fluordurol;Tetramethyl-fluor-benzol;

Chemical Property of 2,3,5,6-TetraMethylfluorobenzene

Chemical Property:

• Melting Point: 54.5-56.1 °C
• Boiling Point: 202.9±9.0 °C(Predicted)
• PSA: 0.00000
• Density: 0.958±0.06 g/cm3(Predicted)
• LogP: 3.05930

Purity/Quality:

97% ^*data from raw suppliers

3-Fluoro-1,2,4,5-tetramethylbenzene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5,6-TetraMethylfluorobenzene

There total 7 articles about 2,3,5,6-TetraMethylfluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

1,2,4,5-tetramethylbenzene (95-93-2) → 1-(trifluoromethyl)-2,3,5,6-tetramethylbenzene (3360-65-4) + 1-fluoro-2,3,5,6-tetramethylbenzene (319-92-6) + 1-(trifluoromethyl)-2,3,4,5-tetramethylbenzene (3360-61-0) + 2,4,5-trimethylbenzyl trifluoroacetate (85649-60-1)

Guidance literature:

With xenon difluoride; trifluoroacetic acid; In dichloromethane; at 25 ℃; for 0.5h;

DOI:10.1021/jo00161a017

Reference yield: 6.0%

1,2,4,5-tetramethylbenzene (95-93-2) + trifluoroacetic acid (76-05-1) → 1-(trifluoromethyl)-2,3,5,6-tetramethylbenzene (3360-65-4) + 1-fluoro-2,3,5,6-tetramethylbenzene (319-92-6) + 1-(trifluoromethyl)-2,3,4,5-tetramethylbenzene (3360-61-0) + 2,4,5-trimethylbenzyl trifluoroacetate (85649-60-1)

Guidance literature:

With xenon difluoride; In dichloromethane; at 25 ℃; for 0.5h;

DOI:10.1021/jo00161a017

Reference yield:

1,2,4,5-tetramethylbenzene (95-93-2) → 1,4-difluoro-2,3,5,6-tetramethylbenzene (10585-06-5) + 1-fluoro-2,3,5,6-tetramethylbenzene (319-92-6)

Guidance literature:

With N-fluorobis(benzenesulfon)imide; at 105 ℃; for 1.67h;

DOI:10.1134/S107042800910008X

upstream raw materials:

p-Aminofluorodurene

1,2,4,5-tetramethylbenzene

trifluoroacetic acid

p-Fluoronitrodurene