11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione

Base Information

• Chemical Name: 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione
• CAS No.: 10417-63-7
• Molecular Formula: C22H30O5
• Molecular Weight: 374.477
• Mol file: 10417-63-7.mol

Synonyms:11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione;16α-Methyl Prednisolone

Chemical Property of 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione

Chemical Property:

• Boiling Point: 571.8±50.0 °C(Predicted)
• PKA: 12.48±0.70(Predicted)
• PSA: 94.83000
• Density: 1.28±0.1 g/cm3(Predicted)
• LogP: 1.80360
• Storage Temp.: Refrigerator
• Solubility.: Dioxane (Slightly), DMSO (Sparingly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

16α-MethylPrednisolone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 16α-Methylprednisolone is the 16α-Methyl analogue of Prednisolone (P703740). 16α-Methylprednisolone is an anti-inflammatory corticosteroid.

Technology Process of 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione

There total 5 articles about 11beta,17alpha,21-Trihydroxy-16alpha-Methyl-1,4-pregnadiene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 11β.17α.21-Trihydroxy-16α-methyl-pregnadien-(1.4)-dion-(3.20) (2597-76-4,10417-63-7,78761-59-8,79645-29-7,85700-75-0,95340-63-9)

Guidance literature:

16α-Methyl-4-pregnen-11β,17α,21-triol-3,20-dion, Nocordiaasteroids (ATCC 9970)-Kultur;

Reference yield:

→ 11α.17α.21-Trihydroxy-16α-methyl-pregnadien-(1.4)-dion-(3.20) (2597-76-4,10417-63-7,78761-59-8,79645-29-7,85700-75-0,95340-63-9)

Guidance literature:

Mikrobiol. Herst. aus 17,21-Dihydroxy-16α-methyl-pregn-4-en-3,20-dion durch Aspergillus ochraceus u. Bacillus lentus;

Reference yield:

→ (11S,13S,16S,17R)-11,17-Dihydroxy-17-(2-hydroxy-acetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one (2597-76-4,10417-63-7,78761-59-8,79645-29-7,85700-75-0,95340-63-9)

Guidance literature:

Pregnadien (I), wss. HOAc;

Downstream raw materials:

16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate

17α,21-dihydroxy-16α-methyl-1,4,9(11)-pregnatriene-3,20-dione 21-acetate

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