5-(BroMoMethyl)-3-(4-nitrophenyl)isoxazole

Base Information

Chemical Name:5-(BroMoMethyl)-3-(4-nitrophenyl)isoxazole
CAS No.:927188-96-3
Molecular Formula:C10H7BrN2O3
Molecular Weight:283.081
Hs Code.:
Mol file:927188-96-3.mol

Synonyms:5-Bromomethyl-3-(4-nitrophenyl)-isoxazole;METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE;

Suppliers and Price of 5-(BroMoMethyl)-3-(4-nitrophenyl)isoxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 5-(BroMoMethyl)-3-(4-nitrophenyl)isoxazole

Chemical Property:

PSA：71.85000
LogP:3.66790

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(BroMoMethyl)-3-(4-nitrophenyl)isoxazole

There total 5 articles about 5-(BroMoMethyl)-3-(4-nitrophenyl)isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.5%

: 3-(4-nitrophenyl)-5-hydroxymethylisoxazole

: 927188-96-3
5-(bromomethyl)-3-(4-nitrophenyl)isoxazole

Guidance literature:: With phosphorus tribromide; In chloroform; at -10 - 20 ℃;
DOI:10.1007/BF03246058

Reference yield: 53.9%

: 106-96-7
propargyl bromide

: 1011-84-3
4-nitrobenzohydroximoyl chloride

: 927188-96-3
5-(bromomethyl)-3-(4-nitrophenyl)isoxazole

Guidance literature:: With triethylamine; In dichloromethane; at -10 - 20 ℃;
DOI:10.1021/jf200395g

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 927188-96-3
5-(bromomethyl)-3-(4-nitrophenyl)isoxazole

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine; hydroxylamine hydrochloride / ethanol

2: hydrogenchloride; N-chloro-succinimide / water; ethyl acetate

3: ethyl acetate; toluene

With pyridine; hydrogenchloride; N-chloro-succinimide; hydroxylamine hydrochloride; In ethanol; water; ethyl acetate; toluene;
DOI:10.1021/op100013m