1-Bromo-3-(tert-butyl)-5-fluorobenzene

Base Information

Chemical Name:1-Bromo-3-(tert-butyl)-5-fluorobenzene
CAS No.:1123172-38-2
Molecular Formula:C10H12BrF
Molecular Weight:231.108
Hs Code.:2902900000
DSSTox Substance ID:DTXSID201250682
Mol file:1123172-38-2.mol

Synonyms:1-Bromo-3-(tert-butyl)-5-fluorobenzene;1123172-38-2;1-bromo-3-tert-butyl-5-fluorobenzene;1-TERT-BUTYL-3-BROMO-5-FLUOROBENZENE;C10H12BrF;SCHEMBL1725233;NEZOQSYMVSKUSO-UHFFFAOYSA-N;DTXSID201250682;Bromo-3-tert-butyl-5-fluorobenzene;YUB17238;MFCD13193246;AKOS024258322;DS-7395;SB18044;1-bromo-3-tert-butyl-5-fluoro-benzene;CS-0054524;EN300-199374;1-Bromo-3-(1,1-dimethylethyl)-5-fluorobenzene;F1905-6451

Suppliers and Price of 1-Bromo-3-(tert-butyl)-5-fluorobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Bromo-3-(tert-butyl)-5-fluorobenzene
100mg
$ 330.00

TRC
1-Bromo-3-(tert-butyl)-5-fluorobenzene
50mg
$ 220.00

Matrix Scientific
1-Bromo-3-tert-butyl-5-fluorobenzene 95%+
1g
$ 611.00

Matrix Scientific
1-Bromo-3-tert-butyl-5-fluorobenzene 95%+
5g
$ 2015.00

Matrix Scientific
1-Bromo-3-tert-butyl-5-fluorobenzene 95%+
2.500g
$ 1334.00

Crysdot
1-Bromo-3-(tert-butyl)-5-fluorobenzene 95+%
5g
$ 1099.00

Crysdot
1-Bromo-3-(tert-butyl)-5-fluorobenzene 95+%
1g
$ 376.00

Chemenu
1-bromo-3-(tert-butyl)-5-fluorobenzene 95%
1g
$ 355.00

Chemenu
1-bromo-3-(tert-butyl)-5-fluorobenzene 95%
5g
$ 1038.00

Apolloscientific
1-bromo-3-tert-butyl-5-fluorobenzene 95+%
1g
$ 484.00

Total 11 raw suppliers

Chemical Property of 1-Bromo-3-(tert-butyl)-5-fluorobenzene

Chemical Property:

Boiling Point:207.4±20.0 °C(Predicted)
PSA：0.00000
Density:1.309±0.06 g/cm3(Predicted)
LogP:3.88570
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:230.01064
Heavy Atom Count:12
Complexity:150

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-3-(tert-butyl)-5-fluorobenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=CC(=C1)Br)F

Technology Process of 1-Bromo-3-(tert-butyl)-5-fluorobenzene

There total 7 articles about 1-Bromo-3-(tert-butyl)-5-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 2-bromo-4-tert-butyl-6-(trimethylsilyl)phenyl triflate

: 1123172-38-2
1-bromo-3-(tert-butyl)-5-fluorobenzene

Guidance literature:: With tetrabutylammonium tetra(tert-butyl alcohol) coordinate fluoride; In tetrahydrofuran; at 20 ℃; for 0.00269444h; regioselective reaction; Inert atmosphere; Flow reactor;
DOI:10.1248/cpb.c18-00578

Reference yield:

: 1123173-10-3
2-bromo-4-tert-butyl-6-fluoro-phenylamine

: 1123172-38-2
1-bromo-3-(tert-butyl)-5-fluorobenzene

Guidance literature:: 2-bromo-4-tert-butyl-6-fluoro-phenylamine; With tert.-butylnitrite; In N,N-dimethyl-formamide; at 60 ℃; for 4h;

With boron trifluoride diethyl etherate; In N,N-dimethyl-formamide; at 25 ℃; for 0.5h;

With water; In N,N-dimethyl-formamide; at 0 ℃;

Reference yield:

: 1644527-00-3
2-(3-bromo--5-(tert-butyl)phenyl)--4,4,5,5--tetramethyl--1,3,2-dioxaborolane

: 1123172-38-2
1-bromo-3-(tert-butyl)-5-fluorobenzene

Guidance literature:: 2-(3-bromo--5-(tert-butyl)phenyl)--4,4,5,5--tetramethyl--1,3,2-dioxaborolane; With potassium tert-butylate; In methanol; at 20 ℃; for 2h; Inert atmosphere;

With silver trifluoromethanesulfonate; In acetone; at 0 ℃; for 0.5h; Inert atmosphere;

In acetone; at 20 ℃; for 1h; Inert atmosphere; Molecular sieve;
DOI:10.1002/anie.201404436