EsoMeprazole related substance H431/41

Base Information

Chemical Name:EsoMeprazole related substance H431/41
CAS No.:1227380-90-6
Molecular Formula:C16H15N3O4
Molecular Weight:313.31
Hs Code.:2933990090
Mol file:1227380-90-6.mol

Synonyms:1-(5-Methoxy-1H-benzo[d]iMidazol-2-yl)-3,5-diMethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid, aMMonia salt;EsoMeprazole related substance H431/41;1,4-Dihydro-1-(5-Methoxy-1H-benziMidazol-2-yl)-3,5-diMethyl-4-oxo-2-Pyridinecarboxylic Acid;1,4-Dihydro-1-(6-methoxy-1H-benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-pyridinecarboxylic acid;1-(6-Methoxy-1H-benzo[d]iMidazol-2-yl)-3,5-diMethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid;1-(5-Methoxy-1H-benzo[d]iMidazol-2-yl)-3,5-diMethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Suppliers and Price of EsoMeprazole related substance H431/41

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(6-Methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylicacid 95+%
100mg
$ 1320.00

Chemenu
1-(6-Methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylicacid 95%
100mg
$ 1234.00

Alichem
1-(6-Methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylicacid
100mg
$ 1438.80

Total 24 raw suppliers

Chemical Property of EsoMeprazole related substance H431/41

Chemical Property:

Boiling Point:537.0±60.0 °C(Predicted)
PKA:-1.45±0.20(Predicted)
PSA：97.21000
Density:1.419
LogP:2.03740

Purity/Quality:

99%, ^*data from raw suppliers

1-(6-Methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of EsoMeprazole related substance H431/41

There total 3 articles about EsoMeprazole related substance H431/41 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: C₁₆H₁₄N₄O₂

: 1227380-90-6
1-(5-methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Guidance literature:: With water; In water; at 42 ℃;
DOI:10.1016/j.molstruc.2021.132315

Reference yield:

: 73590-58-6
omeprazole

: 1227380-90-6
1-(5-methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Guidance literature:: omeprazole; With water; In acetonitrile; at 20 - 75 ℃; for 21h; pH=3.6; Aqueous phosphate buffer;

With sodium hydroxide; In water; pH=7 - 8;

Reference yield:

: C₈H₇N₂O^(1-)*Na⁽¹⁺⁾

: 119730-01-7
2-chloro-5-methoxy-1H-indole

: 1227380-90-6
1-(5-methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutylammomium bromide / acetone; water / 20 °C

2: water / water / 42 °C

With tetrabutylammomium bromide; water; In water; acetone;
DOI:10.1016/j.molstruc.2021.132315