Acetic acid, 2-[5-(2-chlorophenyl)-7-ethyl-3H-thieno[2,3-e]-1,4-diazepin-2-yl]hydrazi de

Base Information

• Chemical Name: Acetic acid, 2-[5-(2-chlorophenyl)-7-ethyl-3H-thieno[2,3-e]-1,4-diazepin-2-yl]hydrazi de
• CAS No.: 40054-72-6
• Molecular Formula: C17H17ClN4OS
• Molecular Weight: 360.867
• Mol file: 40054-72-6.mol

Synonyms:

Chemical Property of Acetic acid, 2-[5-(2-chlorophenyl)-7-ethyl-3H-thieno[2,3-e]-1,4-diazepin-2-yl]hydrazi de

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid, 2-[5-(2-chlorophenyl)-7-ethyl-3H-thieno[2,3-e]-1,4-diazepin-2-yl]hydrazi de

There total 3 articles about Acetic acid, 2-[5-(2-chlorophenyl)-7-ethyl-3H-thieno[2,3-e]-1,4-diazepin-2-yl]hydrazi de which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]1,4-diazepin-2-one (33671-37-3) → 5-(2-chloro-phenyl)-7-ethyl-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one acetylhydrazone (40054-72-6)

Guidance literature:

Multi-step reaction with 2 steps

1: P₂S₅, Py / 1 h / 80 °C

2: ethanol / 2 h / Heating

With pyridine; tetraphosphorus decasulfide; In ethanol;

Reference yield:

5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-thione (40054-40-8) → 5-(2-chloro-phenyl)-7-ethyl-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one acetylhydrazone (40054-72-6)

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄*H₂O / methanol / Ambient temperature

2: Et₃N / CHCl₃ / Ambient temperature

With hydrazine hydrate; triethylamine; In methanol; chloroform;

Reference yield:

acetic anhydride (108-24-7) + 5-(2-chloro-phenyl)-7-ethyl-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one hydrazone (40054-43-1) → 5-(2-chloro-phenyl)-7-ethyl-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one acetylhydrazone (40054-72-6)

Guidance literature:

With triethylamine; In chloroform; Ambient temperature;

upstream raw materials:

acetic anhydride

5-(2-chloro-phenyl)-7-ethyl-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one hydrazone

5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-thione

5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]1,4-diazepin-2-one

Refernces