PRX-08066 free base

Base Information

Chemical Name:PRX-08066 free base
CAS No.:866206-54-4
Molecular Formula:C₁₉H₁₇ClFN₅S
Molecular Weight:401.895
Hs Code.:
UNII:82SK298EBU
ChEMBL ID:CHEMBL513994
DSSTox Substance ID:DTXSID60235710
Metabolomics Workbench ID:149525
Nikkaji Number:J2.933.073E
Pharos Ligand ID:6CFVHSUYN85J
Wikidata:Q44793
Wikipedia:PRX-08066
Mol file:866206-54-4.mol

Synonyms:5-((4-(6-chlorothieno(2,3-d)pyrimidin-4-ylamino)piperidin-1-yl)methyl)-2-fluorobenzonitrile;PRX 08066;PRX-08066;PRX08066

Suppliers and Price of PRX-08066 free base

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
PRX 08066
100mg
$ 1848.00

DC Chemicals
PRX-08066 >98%
1 g
$ 2700.00

Crysdot
PRX-08066 98+%
5mg
$ 262.00

ChemScene
PRX-08066 97.04%
25mg
$ 570.00

ChemScene
PRX-08066 97.04%
10mg
$ 280.00

ChemScene
PRX-08066 97.04%
50mg
$ 990.00

ChemScene
PRX-08066 97.04%
5mg
$ 190.00

Biosynth Carbosynth
PRX 08066
50 mg
$ 647.50

Biosynth Carbosynth
PRX 08066
10 mg
$ 185.00

ApexBio Technology
PRX-08066
5mg
$ 210.00

Total 15 raw suppliers

Chemical Property of PRX-08066 free base

Chemical Property:

PSA：93.08000
Density:1.44
LogP:4.44288
Solubility.:≥20.1 mg/mL in DMSO with ultrasonic; insoluble in H2O; ≥2.85 mg/mL in EtOH with gentle warming
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:401.0877226
Heavy Atom Count:27
Complexity:552

Purity/Quality:

99%, ^*data from raw suppliers

PRX 08066 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N
Recent ClinicalTrials:An Open-Label Study to Evaluate the Safety and Efficacy of PRX-08066 in Patients With Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease
Uses PRX 08066 is a class 2 receptor antagonist which may be used in the treatment of pulmonary diseases.

Technology Process of PRX-08066 free base

There total 1 articles about PRX-08066 free base which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: