IOX2

Base Information

Chemical Name:IOX2
CAS No.:931398-72-0
Molecular Formula:C₁₉H₁₆N₂O₅
Molecular Weight:352.346
Hs Code.:
Mol file:931398-72-0.mol

Synonyms:N-[(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl)carbonyl]glycine; IOX2

Suppliers and Price of IOX2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
IOX 2
25mg
$ 446.00

TRC
IOX2
100mg
$ 525.00

Tocris
IOX2 ≥99%(HPLC)
50
$ 962.00

Tocris
IOX2 ≥99%(HPLC)
10
$ 234.00

Sigma-Aldrich
IOX2 ≥98% (HPLC)
5mg
$ 99.90

Sigma-Aldrich
IOX2 ≥98% (HPLC)
25mg
$ 403.00

Matrix Scientific
2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)aceticacid 97%
250mg
$ 1620.00

Matrix Scientific
2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)aceticacid 97%
100mg
$ 900.00

DC Chemicals
IOX2 >98%
250 mg
$ 650.00

DC Chemicals
IOX2 >98%
100 mg
$ 350.00

Total 74 raw suppliers

Chemical Property of IOX2

Chemical Property:

Boiling Point:642.8±55.0 °C(Predicted)
PKA:3.61±0.10(Predicted)
PSA：108.63000
Density:1.470±0.06 g/cm3(Predicted)
LogP:1.96070
Storage Temp.:2-8°C
Solubility.:DMSO: soluble5mg/mL, clear (warmed)

Purity/Quality:

99%, ^*data from raw suppliers

IOX 2 ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Uses IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM. IOX2 has been used as PHD inhibitor to induce pseudo-hypoxia.

Technology Process of IOX2

There total 2 articles about IOX2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 6000-44-8
sodium glycinate

: 130058-54-7
ethyl 4-hydroxy-2-oxo-1-(phenylmethyl)-1,2-dihydro-3-quinolinecarboxylate

: 931398-72-0
N-[[1,2-dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine

Guidance literature:: sodium glycinate; ethyl 4-hydroxy-2-oxo-1-(phenylmethyl)-1,2-dihydro-3-quinolinecarboxylate; In ethanol; at 150 - 200 ℃; for 0.116667h; Microwave;

With hydrogenchloride; In ethanol; water; Product distribution / selectivity;