5-Bromo-2'-O-methyluridine

Base Information

Chemical Name:5-Bromo-2'-O-methyluridine
CAS No.:34218-83-2
Molecular Formula:C10H13BrN2O6
Molecular Weight:337.12402
Hs Code.:
Mol file:34218-83-2.mol

Synonyms:5-Bromo-2'-O-methyluridin;5-Bromo-1-((2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione;

Suppliers and Price of 5-Bromo-2'-O-methyluridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-2''-O-methyluridine
10g
$ 1260.00

TRC
5-Bromo-2''-O-methyluridine
1g
$ 160.00

Total 12 raw suppliers

Chemical Property of 5-Bromo-2'-O-methyluridine

Chemical Property:

PSA：113.78000
LogP:-1.43530

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2''-O-methyluridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 5-Bromo-2''-O-methyluridine is an analog of Uridine (U829910) and is used as a reagent in the synthesis of RNA containing rigid and nonpertubing cytidine-derived spin labels.

Technology Process of 5-Bromo-2'-O-methyluridine

There total 4 articles about 5-Bromo-2'-O-methyluridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 2140-76-3
2'-O-methyluridine

: 34218-83-2
5-bromo-2'-O-methyluridine

Guidance literature:: With sodium azide; bromoisocyanuric acid monosodium salt; In water; acetonitrile; at 20 ℃; for 1.5h;
DOI:10.3390/molecules181012740

Reference yield: 89.0%

: 1391914-06-9
5-bromo-3',5'-O-benzoyl-2'-O-methyluridine

: 34218-83-2
5-bromo-2'-O-methyluridine

Guidance literature:: With ammonia; In methanol; at 20 ℃; for 96h; Inert atmosphere;
DOI:10.1002/jlcr.2919

Reference yield:

: 632367-79-4,38791-39-8
1,3,5-di-O-benzoyl-2-O-methyl-α/β-D-ribofuranose

: 34218-83-2
5-bromo-2'-O-methyluridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: N,O-bis-(trimethylsilyl)-acetamide / acetonitrile / 0.5 h / Inert atmosphere; Reflux

1.2: 2 h / Inert atmosphere; Reflux

2.1: ammonia / methanol / 96 h / 20 °C / Inert atmosphere

With N,O-bis-(trimethylsilyl)-acetamide; ammonia; In methanol; acetonitrile;
DOI:10.1002/jlcr.2919